Accepted Poster Presentations

LIST OF E-POSTERS

Please note that we do not accept any session, abstract, and title changes from 15 July onwards

The program of the 11th World Congress on Alternatives and Animal Use in the Life Sciences (WC11) will be virtual due to continued COVID-19 imposed restrictions, and will be spread over a two-week period, from 23 August - 2 September 2021.

As the platform will open on 10 August 2021, all posters will be available for poster viewings from 10 August 2021 until 2 September 2021.

The congress has two dedicated poster sessions:

  1. Friday 27 August 2021: 6 PM - 7.30 PM
  2. Tuesday 31 August 2021: 5.15 PM - 6.15 PM

During these two poster sessions, you can enter the virtual room of the poster presenter to ask questions or discuss the poster. Outside the poster session hours, you can visit the poster profile and ask questions to the presenter via chat.

Theme 1: Safety

  • P5: IN VITRO APPROACH FOR ASSESSING RESPIRATORY TOXICITY IN HUMAN LUNG CELLS
    Amy J Clippinger (Abstract ID: 43)
  • P7: EVALUATION OF CARCINOGENICITY POTENTIAL IN TWO TRIAZOLE PESTICIDES USING THE RAPID PARTIAL HEPATECTOMY BIOASSAY MODEL
    Chun-Hung Yang (Abstract ID: 59)
  • P20: USG & RJ LEE IN-VITRO STUDY ON THE BIOPERSISTENCE OF RESPIRABLE MINERAL FIBERS WITH EXISTING AND REFINED TEST METHODS
    Megan Piotrowski (Abstract ID: 116)
  • P22: WORKSHOP ON THE IMPLEMENTATION OF NEXT GENERATION RISK ASSESSMENT (NGRA) FOR SYSTEMIC TOXICITY
    Mabel Cotter (Abstract ID: 119)
  • P25: THE EX VIVO EYE IRRITATION TEST (EVEIT) SYSTEM IN THE DISTINCTION BETWEEN SLIGHT AND SEVERE CORROSIVES
    Markus Glaudo (Abstract ID: 124)
  • P28: RETHINKING CARCINOGENICITY ASSESSMENT FOR AGROCHEMICALS
    Gina Hilton (Abstract ID: 129)
  • P29: DIFFERENTIAL INFLUENCE OF STREPTOCOCCUS MITIS ON HOST RESPONSE TO METALS IN RECONSTRUCTED HUMAN SKIN AND ORAL MUCOSA
    Sue Gibbs (Abstract ID: 130)
  • P30: THE INTRODUCTION OF NEWLY DEVELOPED IN CHEMICO ALTERNATIVE ASSAY, SPECTRO-DPRA, WHICH IMPROVES ORIGINAL DPRA.
    Bae-Hwan Kim (Abstract ID: 132)
  • P32: EXAMINING THE EVIDENCE OF NON-MONOTONIC DOSE-RESPONSE IN ANDROGEN RECEPTOR AGONISM HTS ASSAY
    Kyrylo Klimenko (Abstract ID: 136)
  • P36: DEVELOPMENT OF AN IN-VITRO TESTING BATTERY TO ASSESS BIOCOMPATIBILITY OF MEDICAL DEVICES
    Angelika Wlodarczyk (Abstract ID: 148)
  • P50: A NOVEL STRATEGY COMBINING ITS AND READ-ACROSS TO PREDICT THE SKIN SENSITIZATION POTENCY OF CHEMICALS
    Kanako Nakayama (Abstract ID: 175)
  • P52: A VALIDATION STUDY OF THE IATA-BASED READ-ACROSS IN NEPHROTOXICITY OF AMINOPHENOLS
    Keita Yoshihara (Abstract ID: 177)
  • P58: TOXICITY OF TOPICALLY APPLIED DRUGS BEYOND SKIN IRRITATION: STATIC SKIN MODEL VS TWO ORGANS-ON-A-CHIP
    Renata Spagolla Napoleão Tavares (Abstract ID: 187)
  • P60: A NOVEL MICROFLUIDIC PLATFORM FOR PULMONARY NANOPARTICLE EXPOSURE
    Flora Marta Kiss (Abstract ID: 192)
  • P61: NEXT GENERATION RISK ASSESSMENT OF HUMAN EXPOSURE TO ANTI-ANDROGENS USING NEWLY DEFINED COMPARATOR COMPOUND VALUES
    Tessa van Tongeren (Abstract ID: 193)
  • P65: RAINBOWFLOW CHIP: AN IMPEDANCE-BASED BIOSENSOR FOR CHEMICAL HAZARD ASSESSMENT WITH FISH CELL LINES AT ITS CORE
    Jenny Maner (Abstract ID: 200)
  • P66: VERIFICATION OF THE APPLICABLE DOMAIN OF REACTIVE OXYGEN SPECIES (ROS) ASSAY FOR DEVELOPING PHOTOSAFETY COSMETIC INGREDIENTS
    Takumi Nukaga (Abstract ID: 201)
  • P68: A NOVEL 3D CELL-BASED REACTIVITY ASSAY DEMONSTRATES CAUSAL LINK BETWEEN GLUTATHIONE STATUS AND CYTOTOXICITY
    Radina Kostadinova (Abstract ID: 206)
  • P75: DEVELOPMENT OF A RELIABLE AND REPRODUCIBLE IN VITRO TEST SYSTEM FOR MEASURING FIBRE DISSOLUTION IN BIOLOGICALLY RELEVANT FLUIDS
    Matthew Boyles (Abstract ID: 216)
  • P78: SKINETHIC™ HCE TIME-TO-TOXICITY: THE FIRST INDIVIDUAL METHOD FORMALLY CONSIDERED BY THE OECD FOR DISCRIMINATING ON ITS OWN THE THREE UN GHS OCULAR HAZARD CATEGORIES
    Nathalie Alépée (Abstract ID: 219)
  • P80: COSMETICS EUROPE EYE PROGRAM: APPLICATION OF TWO DEFINED APPROACHES FOR OCULAR TOXICITY PREDICTIONS BASED ON IN VITRO BOTTOM-UP APPROACH ON 4 CASE STUDIES
    Nathalie Alépée (Abstract ID: 221)
  • P81: THE BOTANICAL SAFETY CONSORTIUM’S STRATEGY FOR DEVELOPING A ROBUST FRAMEWORK OF GENOTOXICITY ASSAYS FOR SAFETY ASSESSMENT OF BOTANICAL SUBSTANCES
    Kristine L. Witt (Abstract ID: 223)
  • P85: STUDY ON APPLICABILITY TO POORLY WATER-SOLUBLE SENSITIZING SUBSTANCES IN C-SPRA
    Hidefumi Ikeda (Abstract ID: 232)
  • P88: EVALUATION OF SKIN SENSITIZATION POTENTIAL OF PROTEINS USING DIFFERENTIATED THP-1 CELLS
    Yumi Miura (Abstract ID: 240)
  • P90: HEATED TOBACCO PRODUCTS HAVE LOWER CARDIOTOXIC POTENTIAL WHEN COMPARED TO COMBUSTED CIGARETTES IN HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES
    Liam Simms (Abstract ID: 243)
  • P91: NEW INSIGHTS IN READ ACROSS USING NEW APPROACH METHODS
    Catherine Mahony (Abstract ID: 247)
  • P92: ASSESSING THE REPRODUCIBILITY OF PUBLISHED PHYSIOLOGICALLY-BASED KINETIC MODELS
    Courtney Thompson (Abstract ID: 248)
  • P95: USE OF 3D HUMAN LIVER MICROTISSUES TO ASSESS HEPATOTOXICITY OF BIOLOGICS
    Annie Delaunois (Abstract ID: 253)
  • P96: DISRUPTION OF CELLULAR MIGRATION/ADHESION AS COMMON KEY EVENT IN DRUG-INDUCED LIVER INJURY; OPTIONS FOR NEW IN VITRO TESTING STRATEGIES.
    Raymond Pieters (Abstract ID: 254)
  • P97: USE OF A DYNAMIC SKIN AND LIVER CO-CULTURE MODEL TO INVESTIGATE THE EFFECT OF APPLICATION ROUTE ON THE METABOLISM OF THE HAIR DYE, 4-AMINO-2-HYDROXYTOLUENE
    Thi Phuong Tao (Abstract ID: 256)
  • P98: UPDATED DERMAL SENSITISATION THRESHOLDS DERIVED USING AN IN SILICO EXPERT SYSTEM AND AN EXPANDED LOCAL LYMPH NODE ASSAY DATASET
    Martyn L. Chilton (Abstract ID: 261)
  • P99: NEXT GENERATION RISK ASSESSMENT APPROACH FOR INHALATION EXPOSURES: POLYMER CASE STUDIES
    Maria Teresa Baltazar (Abstract ID: 263)
  • P100: IDENTIFYING AND CHARACTERIZING STRESS PATHWAYS OF CONCERN FOR CONSUMER SAFETY IN NEXT GENERATION RISK ASSESSMENT
    Maria Teresa Baltazar (Abstract ID: 264)
  • P102: PROPOSAL OF A NEW APPLICABILITY DOMAIN OF VITRIGEL-EIT (EYE IRRITANCY TEST) METHOD UTILIZING THE PH LEVEL AND LIGHT ABSORBANCE OF TEST CHEMICAL PREPARATIONS
    Toshiaki Takezawa (Abstract ID: 269)
  • P105: DEVELOPMENT OF IN VITRO MICRONUCLEI ASSAY USING 3D HUMAN RECONSTRUCTED SMALL INTESTINAL EPITHELIUM FOR GENOTOXICITY TESTING
    Hui Kheng Lim (Abstract ID: 272)
  • P106: A NEXT GENERATION RISK ASSESSMENT CASE STUDY FOR COUMARIN IN HYPOTHETICAL COSMETIC PRODUCTS
    Sophie Cable (Abstract ID: 273)
  • P107: USE OF ASSAY READY KERATINOSENS® CELLS TO TEST FOR SKIN SENSITIZATION
    Lukas Focke (Abstract ID: 274)
  • P111: DEVELOPMENT AND APPLICATION OF A NEXT GENERATION RISK ASSESSMENT FRAMEWORK (NGRA) FOR THE EVALUATION OF SKIN SENSITISATION OF COSMETIC INGREDIENTS
    Martina Klaric (Abstract ID: 285)
  • P115: PRIMARY OR IPSC-DERIVED CELL-BASED CYTOTOXICITY ASSAYS TO ASSESS POTENTIAL SAFETY RISKS OF ENGINEERED T CELL THERAPIES IN VITRO
    Marco Guadagnoli (Abstract ID: 295)
  • P116: GENERATION OF NOVEL, INTEGRATED AND INTERNATIONALLY HARMONISED APPROACHES FOR TESTING METABOLISM DISRUPTING COMPOUNDS (GOLIATH)
    Sebastian Hoffmann (Abstract ID: 296)
  • P120: ESTABLISHMENT OF A RISK ASSESSMENT METHOD AND THRESHOLD OF TOXICOLOGICAL CONCERN (TTC) CONCEPT FOR SKIN SENSITIZATION BY NON-ANIMAL APPROACHES
    Takao Ashikaga (Abstract ID: 305)
  • P121: SKIN SENSITIZATION AND IRRITATION ANALYSIS OF MULTI-HERB EXTRACTIONS USING DPRA, H-CLAT AND CLINICAL CLOSED PATCH METHODS
    Yina Lu (Abstract ID: 307)
  • P124: NEW APPROACH FOR SYSTEMIC TOXICITY HAZARD ASSESSMENT BASED ON ALTERNATIVE METHODS TO ANIMAL TESTING IN SUPPORT OF SAFETY DECISION-MAKING
    Emilie Barbeau (Abstract ID: 311)
  • P128: DEIODINASE 1 IN HUMAN LIVER MICROSOMES IS INHIBITED BY ORGANIC AND INORGANIC GOLD COMPOUNDS AND GOLD NANOPARTICLES
    Andreas Georg Weber (Abstract ID: 316)
  • P129: THE THRESHOLD OF TOXICOLOGICAL CONCERN (TTC) IS A PRAGMATIC RISK ASSESSMENT TOOL FOR THE SAFETY ASSESSMENT OF COSMETIC INGREDIENTS WITH LOW CONSUMER EXPOSURE
    Dagmar Bury (Abstract ID: 317)
  • P130: A NEW GROWTH-FACTOR FREE HUMAN CELL BASED IN VITRO ANGIOGENESIS ASSAY FOR TESTING ANGIOGENESIS INHIBITORS
    Barbara Birk (Abstract ID: 318)
  • P132: MINING RETINOIC ACID PATHWAY RELATED BIOMARKERS OF VERTEBRATE DEVELOPMENTAL TOXICITY IN THE ZEBRAFISH EMBRYO MODEL.
    Laura Samrani (Abstract ID: 322)
  • P133: THE EVALUATION OF REPEATED-DOSE TOXICITY BASED ON A READ-ACROSS METHOD USING MOLECULAR DESCRIPTORS
    Yoshihiro Tochikubo (Abstract ID: 323)
  • P135: OECD APPROVAL IS NOT THE END OF THE STORY – ARE EXISTING TEST METHODS (OECD 442C, D AND E) APPLICABLE TO NANOMATERIALS?
    Barbara Birk (Abstract ID: 326)
  • P136: SENSITIZATION POTENTIAL OF MEDICAL DEVICES DETECTED BY METHODS IN VITRO AND IN VIVO
    Svobodova Lada (Abstract ID: 328)
  • P140: THE GARDPOTENCY ASSAY FOR POTENCY-ASSOCIATED SUBCLASSIFICATION OF CHEMICAL SKIN SENSITIZERS – RATIONALE, METHOD DEVELOPMENT AND RING TRIAL RESULTS OF PREDICTIVE PERFORMANCE AND REPRODUCIBILITY.
    Henrik Johansson (Abstract ID: 334)
  • P142: TOXICITY TESTING IN AN IN VITRO MODEL FOR ANTI-CARCINOGENESIS DEMONSTRATES THE IMPROVED PREVENTIVE EFFECTS OF COMBINATIONS OF BIOACTIVE COMPOUNDS AS COMPARED TO SINGLE COMPOUNDS
    Simone van Breda (Abstract ID: 338)
  • P146: RELIABLE AND TRULY ANIMAL-FREE SKIN SENSITIZATION TESTING – ADAPTION OF THE IN VITRO GARDSKIN ASSAY TO ANIMAL FREE CONDITIONS
    Andy Forreryd (Abstract ID: 346)
  • P147: HAZARD ASSESSMENT OF PHOTOALLERGENS USING GARD™SKIN
    Andy Forreryd (Abstract ID: 348)
  • P148: PRACTICAL APPLICATION OF IN SILICO APPROACHES IN NEXT GENERATION RISK ASSESSMENT FOR CONSUMER PRODUCTS
    Steve Gutsell (Abstract ID: 349)
  • P149: FRAMEWORK FOR PHYSIOLOGICALLY-BASED KINETICS (PBK) MODELLING IN THE NEXT GENERATION RISK ASSESSMENT (NGRA) OF CONSUMER GOODS.
    Tom Moxon (Abstract ID: 352)
  • P150: AN IN VITRO MICROFLUIDIC MODEL OF THE HUMAN CARDIOVASCULAR SYSTEM FOR USE IN SCREENING APPLICATIONS – ASSESSMENT OF MONOCYTE-TO-ENDOTHELIAL CELL ADHESION AND CYTOKINE ANALYSIS
    Gina Smith (Abstract ID: 357)
  • P151: NEXT GENERATION RISK ASSESSMENT FOR SKIN ALLERGY: 0.1% COUMARIN IN FACE CREAM AB INITIO CASE STUDY
    Gavin Maxwell (Abstract ID: 358)
  • P154: VALIDATION OF THE USEFULNESS OF IN SILICO PROFILERS AND METABOLIC SIMULATORS TO CHEMICAL GROUPING FOR READ-ACROSS FOR REPEATED DOSE TOXICITY
    Yuki Sakuratani (Abstract ID: 368)
  • P155: COMPARISON OF TOXICITY OF BIOCIDES IN RECONSTRUCTED EPIDERMIS AND AIRWAY MODELS
    Jee-Hyun Hwang (Abstract ID: 369)
  • P156: DEVELOPMENT OF MECHANISM-BASED HEMATOTOXICITY CATEGORIES FOR READ-ACROSS ASSESSMENT USING AN INTEGRATED TOXICITY DATABASE OF CHEMICAL SUBSTANCES
    Takashi Yamada (Abstract ID: 370)
  • P157: SUCCESSFUL IMPLEMENTATION OF U-SENS™ ASSAY FOR SKIN SENSITIZATION TESTING (OECD TG442E) IN CHINA
    Lizao Chen (Abstract ID: 372)
  • P158: A READY-TO-USE INTEGRATED IN VITRO SKIN CORROSION AND IRRITATION TESTING STRATEGY USING EPISKIN™ MODEL IN CHINA
    Nan LI (Abstract ID: 374)
  • P159: MULTI-CENTER VALIDATION OF EPISKIN™ MICRONUCLEUS ASSAY: A 3D APPROACH FOR THE ASSESSMENT OF GENOTOXICITY POTENTIAL
    Lizao Chen (Abstract ID: 375)
  • P161: LIVER-SPECIFIC TRANSGENIC ZEBRAFISH USING FLUORESCENT CASPASE SENSOR FOR VISUALIZING APOPTOSIS
    Seokjoo Yoon (Abstract ID: 378)
  • P162: NEPHROTOXICITY PREDICTION AND STRUCTURE-ACTIVITY ANALYSES OF TOXCAST CHEMICALS BASED ON HIGH-THROUGHPUT IMAGE-BASED PHENOTYPIC PROFILING
    James Alastair Miller (Abstract ID: 379)
  • P163: DEVELOPMENT OF A 3D SKIN COMET ASSAY: BUILDING UP THE FOUNDATION FOR HIGHER TIER IN VITRO TESTING BATTERY OF GENOTOXICITY
    QIN QIN (Abstract ID: 380)
  • P164: FULL REPLACEMENT OF REGULATORY SKIN SENSITIZATION TESTING WITH VALIDATED IN VITRO TESTS: INTEGRATING THE KINETIC PEPTIDE REACTIVITY ASSAY INTO THE TEST BATTERY
    Andreas Natsch (Abstract ID: 382)
  • P166: DEVELOPMENT OF PRE- / PRO-HAPTEN EVALUATION SYSTEM USING MODIFIED H-CLAT
    Akiko Baba (Abstract ID: 386)
  • P169: ADVANCING NANOMATERIAL RISK ASSESSMENT BY FULL PHYSICO-CHEMICAL NANOMATERIAL CHARACTERIZATION IN COMPLEX MATRICES AND CORRELATIVE ANALYSIS USING THE NANOPARTICLE SCOPE
    Sandra Verstraelen (Abstract ID: 389)
  • P173: PREDICTIVE ACUTE FISH TOXICITY MODELS AND APPLICABILITY WITHIN THE INDUSTRIAL CONTEXT
    Filippo Lunghini (Abstract ID: 394)
  • P174: IN VITRO EVALUATION OF GENOTOXICITY AND IRRITATION POTENTIAL OF EYE DROPS CONTAINING AQUEOUS PLANT EXTRACTS
    Ilona Zilkowski (Abstract ID: 395)
  • P175: MULTICENTRIC STUDY OF SKINETHIC™ HCE TIME-TO-TOXICITY METHOD FOR SERIOUS EYE DAMAGE/EYE IRRITATION ASSESSMENT
    Nathalie Alépée (Abstract ID: 396)
  • P181: IDENTIFICATION AND CHARACTERIZATION OF THYROID HORMONE DISRUPTORS IN DEVELOPING 3D NEURAL PROGENITOR CELLS IN VITRO
    Jördis Klose (Abstract ID: 403)
  • P184: INVESTIGATION OF NEURODEVELOPMENTAL TOXICITY OF CHINESE HERBAL MEDICINES USING A 3D HUMAN PRIMARY NEURAL PROGENITOR CELL ASSAY IN VITRO
    Jördis Klose (Abstract ID: 406)
  • P189: CYTOTOXICITY OF ZNO MICRO AND NANOPARTICLES ON HACAT AND A549 STUDIED BY MTT, NRU AND LDH VIABILITY ASSAYS
    Montse Mitjans (Abstract ID: 416)
  • P192: IMPROVED TOPICAL GENOTOXICITY ASSESSMENT USING MICRONUCLEUS ASSAY ON 3D RECONSTRUCTED HUMAN EPIDERMISES
    Eric Andres (Abstract ID: 420)
  • P198: DEVELOPMENT OF AN IN VITRO PHOTOSAFETY EVALUATION METHOD UTILIZING INTRACELLULAR ROS PRODUCTION IN THP-1 CELLS
    Akemi Toyoda (Abstract ID: 431)
  • P199: DARTPATHS: DEVELOPMENT OF AN IN SILICO PLATFORM TO ASSESS DEVELOPMENTAL AND REPRODUCTIVE TOXICITY (DART)
    Monique van der Voet (Abstract ID: 432)
  • P200: BENZYL SALICYLATE CASE STUDY: IN-SILICO SCREENING FOR ENDOCRINE DISRUPTOR POTENTIAL
    Melanie Delannoy (Abstract ID: 433)
  • P201: DEVELOPMENT OF A STATISTICAL PREDICTION MODEL FOR SKIN SENSITIZATION BY COMBINING MULTIPLE IN VITRO TESTS
    Yuichiro Goto (Abstract ID: 434)
  • P202: IN VITRO ASSESSMENT OF SENSITIZATION BY A CHROMOPHORE-SOLID PHASE PEPTIDE REACTION ASSAY (C-SPRA) USING MICROBEADS
    Kenji Usui (Abstract ID: 435)
  • P203: HUMAN BASED NEW APPROACH METHODS (NAMS) IN A MEDIUM THROUGHPUT SET UP IMPLEMENTED IN A TEST BATTERY FOR DEVELOPMENTAL NEUROTOXICITY (DNT) TESTING
    Stefan Masjosthusmann (Abstract ID: 436)
  • P205: DEVELOPMENT OF A 3D GENOTOXICITY MODEL FOR ASSESSMENT OF COSMETIC FORMULATIONS
    Jâinah Halliday (Abstract ID: 440)
  • P206: DEVELOPMENT AND VALIDATION OF AN IN VITRO ASSAY TO ASSESS EXTRA MILD PERSONAL CARE FORMULATIONS AND THE GENERATION OF AN INDUSTRY-RELEVANT BENCHMARKING DATABASE
    Fiona Jacobs (Abstract ID: 443)
  • P208: A HUMAN IPSC-BASED IN VITRO NEURONAL NETWORK FORMATION ASSAY TO INVESTIGATE NEURODEVELOPMENTAL TOXICITY OF PESTICIDES
    Kristina Bartmann (Abstract ID: 447)
  • P211: OEM/ODM ENTERPRISE ESTABLISHES ALTERNATIVE METHOD PLATFORM TO PROMOTE THE SUSTAINABLE DEVELOPMENT
    Shasha Ma (Abstract ID: 451)
  • P213: IN VITRO TESTS OF STONE WOOL FIBRES DISSOLUTION
    Denis Okhrimenko (Abstract ID: 453)
  • P223: ASSESSMENT SKIN SENSITIZATION OF PLANT EXTRACTS BY THE DERMAL SENSITIZATION THRESHOLD APPROACH AND TWO IN VITRO TEST METHODS
    Shasha Ma (Abstract ID: 471)
  • P224: TOWARDS MECHANISTIC-BASED ASSESSMENT: RAPID ELUCIDATION OF THE PROTEIN BINDERS OF DIKETONES USING PHENOTYPIC AND PROTEOMIC PROFILING, AND BIOMOLECULAR MODELING
    Lit-Hsin Loo (Abstract ID: 472)
  • P225: RETROSPECTIVE ANALYSIS OF DERMAL TRIPLE PACK DATA
    David G Allen (Abstract ID: 474)
  • P235: A HUMAN CELL BASED SCREEN SUPPORTING WEIGHT OF EVIDENCE APPROACHES FOR THE ACUTE TOXICITY OF COSMETIC INGREDIENTS
    Fiona Jacobs (Abstract ID: 486)
  • P240: IN SILICO AND IN VITRO APPROACHES SUPPORTING TARGET ORGAN SAFETY ASSESSMENT IN PHARMACEUTICAL DRUG DISCOVERY
    Annie Delaunois (Abstract ID: 498)
  • P242: READ-ACROSS CAN INCREASE CONFIDENCE IN THE NEXT GENERATION RISK ASSESSMENT FOR SKIN SENSITISATION: A CASE STUDY WITH RESORCINOL
    Nathalie Alépée (Abstract ID: 500)
  • P243: BEYOND ANIMAL TESTING FOR SKIN SENSITIZATION OF COSMETIC INGREDIENTS: A CASE STUDY WITH PROPYL PARABEN
    Nathalie Alépée (Abstract ID: 502)
  • P245: BISPHENOL A, BISPHENOL F AND BISPHENOL S: THE BAD AND THE UGLY. WHERE IS THE GOOD?
    Sophie Fouyet (Abstract ID: 509)
  • P249: SAFETY OF COSMETIC PERFUMES SCREENED BY A BATTERY OF NOVEL IN VITRO BIOASSAYS COMBINED WITH TARGETED CHEMICAL ANALYSES
    Markéta Dvořáková (Abstract ID: 517)
  • P256: THE MONOCYTE ACTIVATION TEST (MAT): THE ROAD FORWARD FOR PYROGENICITY TEST AND REPLACING THE ANIMAL TESTING
    Shabnam Solati (Abstract ID: 528)
  • P259: ASSURING CONFIDENCE IN NEW APPROACH METHODOLOGIES (NAMS) – A DATA GOVERNANCE CASE STUDY
    Paul Russell (Abstract ID: 535)
  • P261: HUMAN LIVER-ON-A-CHIP AS A MODEL FOR BIOTRANSFORMATION AND CHRONIC TOXICITY STUDIES
    Meike van der Zande (Abstract ID: 537)
  • P262: TOWARDS THE DEVELOPMENT OF ANIMAL PRODUCT-FREE IN VITRO SYSTEMS FOR NGRA OF CONSUMER GOODS
    Paul Russell (Abstract ID: 538)
  • P264: COMPARISON OF CYTOCHROME P450 EXPRESSION, INDUCTION AND ACTIVITY BETWEEN HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED INTESTINAL ORGANOIDS AND CACO-2 CELLS
    Meike van der Zande (Abstract ID: 540)
  • P266: EVALUATION OF A TRI-CULTURE GUT-ON-CHIP MODEL FOR LONG TERM EXPOSURE STUDIES
    Meike van der Zande (Abstract ID: 542)
  • P272: HOW THE GOOD IN VITRO METHOD PRACTICES GUIDANCE DOCUMENT CAN HELP IMPLEMENT NEW TOXICOLOGICAL APPROACHES: A CASE STUDY IN CHINA
    Sandra Coecke (Abstract ID: 551)
  • P274: APPLICATION OF HUMAN INDUCED PLURIPOTENT STEM CELL CARDIOMYOCYTES (HIPSC-CM) IN PRECLINICAL IN VITRO CARDIOTOXICITY ASSESSMENT: CHALLENGES AND OPPORTUNITIES
    Vitalina Gryshkova (Abstract ID: 554)
  • P275: DEFINING THE REPRODUCIBILITY AND APPLICABILITY DOMAIN OF DEVTOX QUICKPREDICT, A HUMAN PLURIPOTENT STEM CELL-BASED DEVELOPMENTAL TOXICITY ASSAY
    Jessica Ann Palmer (Abstract ID: 555)
  • P277: A TARGETED METABOLOMICS-BASED ASSAY USING HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES IDENTIFIES STRUCTURAL AND FUNCTIONAL CARDIOTOXICITY POTENTIAL
    Jessica Ann Palmer (Abstract ID: 557)
  • P280: THE EXTENT TO WHICH IN VITRO DISTRIBUTION KINETICS DETERMINES DIFFERENCES IN INTRINSIC HEPATIC CLEARANCE BETWEEN ASSAY SETUPS
    Susana Proença (Abstract ID: 560)
  • P281: INTEGRATED STRATEGY FOR EYE IRRITATION ASSESSMENT OF AGROCHEMICAL FORMULATIONS
    María Laura Gutiérrez (Abstract ID: 563)
  • P283: CRISPR-CAS9 GENE EDITING IN CULTURED FISH CELLS – TOWARD A NEW ERA OF MECHANISTIC TOXICOLOGY
    Marina Zoppo (Abstract ID: 565)
  • P284: APPLICATION OF IN SILICO TOOLS DEVELOPED WITHIN LIFE-VERMEER: FOOD CONTACT MATERIALS AS CASE STUDY
    Birgit Mertens (Abstract ID: 566)
  • P285: IDENTIFYING PUTATIVE MODE-OF-ACTIONS FOR ENVIRONMENTAL CHEMICALS USING HIGH-THROUGHPUT PHENOTYPIC PROFILING
    Johanna Nyffeler (Abstract ID: 567)
  • P288: INTERNATIONAL APPROACHES TO IMPLEMENTING ALTERNATIVE TEST METHODS FOR MARINE BIOTOXINS IN SHELLFISH
    Katherine Groff Werchadlo (Abstract ID: 571)
  • P290: THE CHANGING FACE OF CHEMICALS LEGISLATION IN INDIA: OPPORTUNITIES TO MINIMISE TESTING ON ANIMALS
    Ankita Pandey (Abstract ID: 574)
  • P291: TOWARDS IN VITRO-IN VIVO CORRELATIONS OF RESPIRATORY TOXICITY CAUSED BY NANOMATERIALS
    Emilio Di Ianni (Abstract ID: 576)
  • P293: COMPARATIVE STUDY ON GENOTOXIC ACTIVITIES OF DIFFERENT COMPONENTS OF FINE PARTICULATE MATTER (PM2.5) USING IN VITRO BIOASSAYS
    Jing Yang (Abstract ID: 581)
  • P303: TRIPTOLIDE AND ATORVASTATIN SYNERGISTICALLY PROMOTE HEPATOTOXICITY IN CULTURED HEPATOCYTES AND FEMALE SPRAGUE-DAWLEY RATS BY INHIBITING PREGNANE X RECEPTOR-MEDIATED TRANSCRIPTIONAL ACTIVATION OF CYP3A4
    Lili Wang (Abstract ID: 602)
  • P310: EVALUATION OF ANTI-EGFR INDUCED ON- AND TARGET-MEDIATED ADVERSE EFFECTS IN A MICROFLUIDIC 3D HUMAN CO-CULTURE MODEL
    Juliane Hübner (Abstract ID: 615)
  • P313: ENDOCRINE DISRUPTORS – HARMONISING WITH JUST 1R (REPLACEMENT) IN MIND
    Emma Grange (Abstract ID: 621)
  • P316: KEEP IT SIMPLE, SAVE YOUR MONEY AND STICK TO THE PRECLINICAL IN VITRO TOOLS FOR PULMONARY DRUG DEVELOPMENT
    Marius Hittinger (Abstract ID: 626)
  • P317: INVESTIGATION OF ABSORPTION PATHWAYS OF SMALL PLASTIC PARTICLES USING IN VITRO MODELS OF THE HUMAN SMALL INTESTINE
    Kousuke Inamura (Abstract ID: 627)
  • P323: REGRESSION AND CLASSIFICATION MODELS TO PREDICT ORAL RAT ACUTE TOXICITY
    Filippo Lunghini (Abstract ID: 639)
  • P324: NOVEL BIOMARKERS FOR HUMAN CELL LINE ACTIVATION TEST (H-CLAT)
    Aneesh Karkhanis (Abstract ID: 640)
  • P327: ZINC OXIDE NANOPARTICLES DISRUPT AUTOPHAGY AND INDUCE CYTOTOXICITY IN HUMAN KERATINOCYTES BY PERTURBATION OF NRF2 PATHWAY
    Hui Peng (Abstract ID: 645)
  • P329: ASSESSMENT CUMULATIVE CHRONIC IRRITATION BY SINGLE ORGAN CHIP OF SKIN
    Shasha Ma (Abstract ID: 647)
  • P330: PRELIMINARY STUDY ON ASSESSMENT SKIN SENSITIZATION OF MATERIALS IN-CAR BY THE DIRECT PEPTIDE BINDING ASSAY AND THE HUMAN CELL LINE ACTIVATION TEST
    Shasha Ma (Abstract ID: 649)
  • P331: IDENTIFICATION OF KEY TRANSCRIPTION FACTOR NETWORKS MEDIATING VALPROIC ACID-INDUCED MITOCHONDRIAL DYSFUNCTIONING IN PRIMARY HUMAN HEPATOCYTES
    Twan van den Beucken (Abstract ID: 651)
  • P333: EXPOSURE TO AEROSOL OF AN E-VAPOR DEVICE WITH MESH™ TECHNOLOGY HAD A LOWER BIOLOGICAL IMPACT THAN EXPOSURE TO CIGARETTE SMOKE ON HUMAN BRONCHIAL AND ALVEOLAR CULTURE MODELS: AN IN VITRO SYSTEMS TOXICOLOGY ASSESSMENT
    Albert Giralt (Abstract ID: 655)
  • P342: CHARACTERIZATION OF CHEMICAL SUBSTANCES USING CYTOCHROME P450 INHIBITION DATA
    Kouichi Yoshinari (Abstract ID: 674)
  • P343: CIRCULAR RNA IN TOXIC CONDITIONS
    Juan Ochoteco Asensio (Abstract ID: 675)
  • P350: IN VITRO SKIN SENSITISATION ASSAYS: PRACTICAL EXPERIENCES PERFORMING THE DPRA, KERATINOSENS™ AND H-CLAT
    Darren KIDD (Abstract ID: 694)
  • P351: THE DEVELOPMENT OF A 3D HEPATIC SPHEROID MODEL FOR THE PRECLINICAL ASSESSMENT OF NANOBIOMATERIALS FOR BIOMEDICAL APPLICATIONS
    Melissa Anne Tutty (Abstract ID: 697)
  • P360: THE HET-MN (HEN`S EGG TEST FOR MICRONUCLEUS INDUCTION): AN IN VITRO ASSAY REFLECTING SYSTEMIC AVAILABILITY OF TEST COMPOUNDS.
    Kerstin Reisinger (Abstract ID: 712)
  • P366: ANALYSIS OF FRAGRANCE INGREDIENTS IN KINETIC DPRA ASSAY FOR SKIN SENSITIZATION
    Mihwa Na (Abstract ID: 729)
  • P370: STUDY OF LOCOMOTION RESPONSE AND DEVELOPMENT IN ZEBRAFISH (DANIO RERIO) EMBRYOS AND LARVAE EXPOSED TO MYCOTOXINS
    Ana Juan-Garcia (Abstract ID: 735)
  • P372: ZEARALENONE METABOLITES AND BEAUVERICIN MYCOTOXINS ON SH-SY5Y CELLS PRODUCE REACTIVE OXYGEN SPECIES AND ALTER GENE EXPRESSION INVOLVED IN APOPTOSIS AND ESTROGEN RECEPTORS
    Ana Juan-Garcia (Abstract ID: 737)
  • P378: GUIDANCE ON DOSE-SETTING IN REPEATED-DOSE TOXICITY STUDIES; OUTCOME OF AN ECETOC TASK FORCE
    Marco Corvaro (Abstract ID: 747)
  • P386: DEVELOPMENT OF AN “AGITATED” IN-VITRO TEST FOR GLASS FIBRE DISSOLUTION
    Elodie Chaudan (Abstract ID: 757)
  • P387: USING A BONE MARROW MICROPHYSIOLOGICAL SYSTEM TO INFORM ONCOLOGY DRUG-COMBINATION SCHEDULING
    Benedicte Recolin (Abstract ID: 758)
  • P393: TARGETTRI: SAFETY ASSESSMENT AND DE-RISKING OF NOVEL DRUG TARGETS
    Simon Folkertsma (Abstract ID: 772)
  • P394: INTEGRATED APPROACHES TO TESTING AND ASSESSMENT OF CHEMICAL RESPIRATORY SENSITIZERS: SUPPORTING A LIST OF REFERENCE CHEMICALS WITH A WEIGHT-OF-EVIDENCE ASSESSMENT OF AVAILABLE INFORMATION
    Kristie Sullivan (Abstract ID: 773)
  • P397: MACHINE LEARNING BASED META-ANALYSIS USING MULTIPLE TOXICOGENOMICS DATASETS DOES NOT IMPROVE GENOTOXICITY PREDICTION
    Danyel Jennen (Abstract ID: 776)
  • P405: HUMAN IPSC-DERIVED PROXIMAL TUBULAR CELLS-BASED TRANSCRIPTOMICS DATA TO EVALUATE CADMIUM EXPOSURE AT A HIGH TEMPORAL RESOLUTION
    Pranika Singh (Abstract ID: 791)
  • P412: SCREENING OF REPEATED DOSE TOXICITY DATA IN SAFETY EVALUATION REPORTS OF COSMETIC INGREDIENTS ISSUED BY THE SCIENTIFIC COMMITTEE ON CONSUMER SAFETY BETWEEN 2009 AND 2019
    Emma Gustafson (Abstract ID: 800)
  • P413: IN VITRO CELL TRANSFORMATION BIOMARKERS AS CRITERIA FOR EVALUATING POTENTIAL CARCINOGENS
    Maryna Anisovich (Abstract ID: 801)
  • P415: TRICHLOROETHYLENE GLUTATHIONE CONJUGATES: BIOTRANSFORMATION KINETICS AND IMPACT ON OXYGEN CONSUMPTION RATES (OCR) IN HUMAN RENAL PROXIMAL TUBULAR CELLS (RPTEC/TERT1)
    Liliana Monica Santos Capinha (Abstract ID: 803)
  • P416: FUNCTIONAL AND TRANSCRIPTIONAL ASSESSMENT OF ELECTRON TRANSPORT CHAIN (ETC) INHIBITION IN CULTURED HUMAN RENAL PROXIMAL TUBULE CELLS.
    Giada Carta (Abstract ID: 804)
  • P426: ACUTE TOXIC EFFECTS OF RUTHENIUM (II) MERCAPTO AND NAPHTOQUINONES COMPLEXES ON AND ZEBRAFISH EMBRYOS
    Thallita Monteiro Teixeira (Abstract ID: 833)
  • P437: EMULATION OF A HIPSC BASED LIVER-ON-CHIP MODEL FOR RECREATING METABOLIC ZONATION AND INFECTION MODEL
    Kehinde Oluwasegun Aina (Abstract ID: 870)
  • P438: COSMETIC EUROPE’S LONG RANGE SCIENCE STRATEGY NON-ANIMAL SAFETY ASSESSMENT CASE STUDY OF PHENOXYETHANOL IN COSMETICS
    MATTHEW DENT (Abstract ID: 874)
  • P439: THE RTGILL-W1 CELL LINE ASSAY TO PREDICT FISH ACUTE TOXICITY OF WATER SAMPLES AND CHEMICALS (ISO 21115:2019)
    Melanie Fischer (Abstract ID: 875)
  • P441: HPLACENTOX : NEW METHOD FOR ENDOCRINE DISRUPTORS ASSESSMENT USING A HUMAN PLACENTAL MODEL
    Elodie OLIVIER (Abstract ID: 878)
  • P443: EVALUATING THE RELATIVE POTENCY OF PYRROLIZIDINE ALKALOIDS USING IN VITRO TECHNOLOGIES
    Catherine Mahony (Abstract ID: 880)
  • P444: SYNTOX: AN INTERACTIVE APPLICATION FOR DISEASE PHENOTYPE ETIOLOGY EXPLORATIONS
    Richard Alan Currie (Abstract ID: 885)
  • P445: SIMULATION OF DYSTOCIA IN BOVINE AND EQUINE USING MODELS PRESERVED BY THE ELNADY TECHNIQUE.
    Fawzy Elnady (Abstract ID: 863)
  • P447: ESTABLISHMENT OF AN IN VITRO RABBIT NEUROSPHERE MODEL TO EVALUATE NEURODEVELOPMENTAL ADVERSE EFFECTS INDUCED BY INTRA-UTERINE GROWTH RESTRICTION (IUGR) AND TO TEST FUTURE THERAPIES
    Britta Anna Kühne (Abstract ID: 904)
  • P451: TOWARDS AN ADME COMPETENT 4-ORGAN-CHIP
    Beren Atac Wagegg (Abstract ID: 923)
  • P457: RETROSPECTIVE REVIEW ON IN VITRO PHOTOTOXICITY DATA GENERATED IN 3D SKIN MODELS TO SUPPORT DEVELOPMENT OF NEW OECD TEST GUIDELINE
    Helena Kandarova (Abstract ID: 929)
  • P459: BIO-COMPATIBILITY ASSESSMENT OF MEDICAL DEVICES USING RECONSTRUCTED IN VITRO 3D HUMAN CORNEA-LIKE TISSUE MODEL
    Helena Kandarova (Abstract ID: 932)
  • P464: THE MONOCYTE ACTIVATION TEST (MAT): THE ROAD FORWARD FOR PYROGENICITY TEST AND REPLACING THE ANIMAL TESTING
    Shabnam Solati (Abstract ID: 953)
  • P471: QUANTITATIVE SENSITIZING POTENCY ASSESSMENT USING GARDSKIN DOSE-RESPONSE
    Henrik Johansson (Abstract ID: 961)
  • P475: HUMAN-RELEVANT APPROACHES TO ASSESS EYE CORROSION/IRRITATION POTENTIAL OF AGROCHEMICAL FORMULATIONS
    Amy J Clippinger (Abstract ID: 965)
  • P476: ASSESSMENT OF SKIN SENSITIZATION POTENTIAL OF FRAGRANCE INGREDIENTS USING THE U-SENS™ ASSAY
    Isabelle Lee (Abstract ID: 966)
  • P486: BUILDING CONFIDENCE IN USING NEW APPROACH METHODOLOGIES FOR CONSUMER-BASED RISK ASSESSMENT: CHALLENGES AND FUTURE PERSPECTIVES
    Alistair Middleton (Abstract ID: 978)
  • P488: GARD™SKIN AND GARD™POTENCY: A PROOF OF CONCEPT STUDY TO INVESTIGATE THE APPLICABILITY DOMAIN FOR AGROCHEMICAL FORMULATIONS.
    Marco Corvaro (Abstract ID: 980)
  • P489: AN INTEGRATED TESTING STRATEGY (ITS) FOR EVALUATING ACUTE FISH TOXICITY WITH ZEBRAFISH EMBRYO AND OECD QSAR TOOLBOX
    Ying-Jan Wang (Abstract ID: 981)
  • P492: A STUDY ON THE CORRELATION BETWEEN THE HET-CAM AND THE RECONSTRUCTED VAGINAL TISSUE MODEL FOR SAFETY TEST OF FEMININE WASH
    Minseok Choi (Abstract ID: 986)
  • P493: IDENTIFICATION OF SKIN SENSITIZING IMPURITIES IN REACTION MIXTURES BY FLUORESCENT NITROBENZOXADIAZOLE-LABELED GLUTATHIONE
    Gaku Yamamoto (Abstract ID: 987)
  • P495: ASSESSING EXPERIMENTAL UNCERTAINTY IN DEFINED APPROACHES FOR SKIN SENSITZATION
    Susanne Kolle (Abstract ID: 989)
  • P496: CYTOTOXICITY EVALUATION OF TETRABROMOBISPHENOL A AND POLYSTYRENE NANOPLASTICS ON RTGILL-W1 FISH CELLS
    Inés Tejeda (Abstract ID: 990)
  • P502: QUALITY CONTROL OF HEPATIC STEM CELLS DERIVED FROM HUMAN FETAL HEPATOCYTES USING NOVEL NANOPARTICLES
    Seiichi Ishida (Abstract ID: 997)
  • P504: U-SENS™: APC CAN BE USED AS AN ALTERNATIVE IN CASE OF STRONG CHEMICAL-INDUCED AUTOFLUORESCENCE AT THE FITC-SPECIFIC WAVELENGTHS
    Nathalie Alépée (Abstract ID: 999)
  • P505: DEVELOPING A DEFINED APPROACH FOR EYE IRRITATION TESTING
    Neepa Choksi (Abstract ID: 1001)
  • P506: BEATING ORGANS-ON-CHIP AS ADVANCED TOOLS IN DRUG SCREENING: ENGINEERED IN VITRO MODELS OF HUMAN ORGANS AND DISEASES
    Stefano Piazza (Abstract ID: 1002)
  • P507: THYROID DISRUPTION RESCUE OF IODIDE ON A ZEBRAFISH VERTEBRATE MODEL
    María José Mazón (Abstract ID: 1003)
  • P509: VARIABILITY IN THE RABBIT SKIN IRRITATION ASSAY
    John P Rooney (Abstract ID: 1005)
  • P510: DEVELOPMENT OF AN IN SILICO PLATFORM TO ASSESS DEVELOPMENTAL AND REPRODUCTIVE TOXICITY (DART)
    Marjolein Wildwater (Abstract ID: 1006)
  • P511: APPLICATION OF DEFINED APPROACHES FOR SKIN SENSITIZATION TO AGROCHEMICAL PRODUCTS
    Judy Strickland (Abstract ID: 1007)
  • P512: TOXICITY OF THE AEROSOL INGREDIENT ALUMINIUM CHLOROHYDRATE (ACH) IN AN IN VITRO MODEL OF HUMAN ALVEOLAR CELLS
    Emanoela Thá (Abstract ID: 1009)
  • P514: INTEGRATED APPROACH TO EVALUATE SKIN PERMEATION AND SKIN SENSITIZATION OF BACCHARIS TRIMERA (LESS.) DC ASTERACEAE
    Gabriella Lisboa dos Santos (Abstract ID: 1011)
  • P515: DOSE-DEPENDENT CITOTOXICITY OF BISMUTH NANOPARTICLES PRODUCED BY LASIS IN A REFERENCE MAMMALIAN CELL LINE BALB/C 3T3 AND HUMAN MESENCHYMAL STEM CELLS
    Alessandra Melo de Aguiar (Abstract ID: 1013)
  • P523: EVALUATION OF CELLULAR DAMAGE USING IN VITRO INTESTINAL MODELS AFTER EXPOSURE TO TETRABROMOBISPHENOL A AND POLYSTYRENE NANOPLASTICS
    Patricia Soto Bielicka (Abstract ID: 1024)
  • P538: IMPLEMENTATION OF AN IN VITRO TRANSGENIC RODENT (TGR) ASSAY FOR THE DETECTION OF POTENTIAL MUTAGENS AND ASSESSMENT OF THEIR MECHANISM OF ACTION
    Barbara Birk (Abstract ID: 1045)
  • P540: ASSESSING HUMAN CARCINOGENICITY RISK WITHOUT THE RODENT CANCER BIOASSAY
    Amber Goetz (Abstract ID: 1047)
  • P541: WEIGHT OF EVIDENCE APPROACH FOR SKIN SENSITIZATION POTENCY CATEGORIZATION OF FRAGRANCE INGREDIENTS
    Mihwa Na (Abstract ID: 1048)
  • P542: EFFECT OF MINERAL FIBRES ON ACUTE TOXICITY AND INFLAMMATION IN AN IN VITRO MODEL OF HUMAN M0-M1-M2 MACROPHAGES
    Serena Mirata (Abstract ID: 1049)
  • P543: AN ALTERNATIVE IN VITRO APPROACH TO EVALUATE IN HUMAN ENDOTHELIAL CELLS AND MONOCYTES BOTH DIRECT AND INDIRECT CARCINOGENIC EFFECT OF ASBESTOS FIBERS
    Vanessa Almonti (Abstract ID: 1052)
  • P544: IMPEDANCE SPECTROSCOPY AS TOOL TO DETERMINE CONCENTRATION-DEPENDENT EYE IRRITATION EFFECTS
    Nicola Knetzger (Abstract ID: 1053)
  • P546: INTEGRATION OF MACHINE LEARNING AND CHEMINFORMATICS APPROACHES TOWARDS NANOMATERIALS TOXICITY ASSESSMENT
    Bakhtiyor Rasulev (Abstract ID: 1055)
  • P549: A 3D ALVEOLAR IN VITRO MODEL FOR THE PREDICTION OF CHEMICAL RESPIRATORY SENSITIZERS AND IRRITANTS
    Sabina Burla-Mihaescu (Abstract ID: 1058)
  • P552: DEVELOPING A NEW APPROACH TO ASSESS CROP PROTECTION CHEMICAL SAFETY THAT MINIMIZES RELIANCE ON VERTEBRATE TESTING AND PROTECTS HUMAN HEALTH AND THE ENVIRONMENT
    Natalia Ryan (Abstract ID: 1062)
  • P554: TOWARD REGULATORY ACCEPTANCE OF RECOMBINANT FACTOR C BASED ASSAYS IN THE UNITED STATES
    Elizabeth Baker (Abstract ID: 1064)
  • P555: ASSESSMENT SKIN SENSITIZATION OF PLANT EXTRACTS BY THE DERMAL SENSITIZATION THRESHOLD APPROACH AND TWO IN VITRO TEST METHODS
    Tingting Luo (Abstract ID: 1065)
  • P560: DEVELOPMENT OF A PREDICTIVE MODEL FOR INDIVIDUAL SUSCEPTIBILITY TO HEARING LOSS USING HUMAN GENETIC, EXPOSURE AND EPIDEMIOLOGICAL DATA
    Rebecca Clewell (Abstract ID: 1071)
  • P561: AN IN VITRO APPROACH TO DETERMINE THE HUMAN RELEVANCE OF ANTI-SPERMATOGENIC EFFECTS OF AN INDUSTRIAL SOLVENT IN RAT REPRODUCTIVE TOXICITY STUDIES
    Rebecca Clewell (Abstract ID: 1073)
  • P562: POLICY INITIATIVES FOR INTEGRATING NEW APPROACH METHODOLOGIES FOR TESTING PHARMACEUTICALS IN THE UNITED STATES
    Elizabeth Baker (Abstract ID: 1074)
  • P566: DYNAMIC IN VITRO ASSESSMENT OF LUNG EPITHELIAL CELLS UNDER MECHANICAL STRAIN
    Sandeep Keshavan (Abstract ID: 1078)
  • P567: AN INVERTED IN VITRO TRIPLE CULTURE MODEL OF THE HEALTHY AND INFLAMED INTESTINE: ADVERSE EFFECTS OF POLYETHYLENE PARTICLES
    Mathias Busch (Abstract ID: 1079)
  • P568: COMPARISON OF THE EFFECTS OF ENGINEERED NANOMATERIALS IN SIMPLE VERSUS COMPLEX IN VITRO MODELS OF HUMAN INTESTINE
    Angela Kämpfer (Abstract ID: 1080)
  • P569: GAP ANALYSIS OF EFFECT-DIRECTED MONITORING TOOLS FOR RISK ASSESSMENT OF DRINKING WATER
    Valentin De Gussem (Abstract ID: 1081)
  • P572: PERFORMANCE OF THE GHS MIXTURES EQUATION FOR PREDICTING ACUTE ORAL TOXICITY
    Jon Hamm (Abstract ID: 1087)
  • P574: THE USE OF THE HEPARG MICRONUCLEUS ASSAY FOR THE ASSESSMENT OF IN VITRO GENOTOXICITY POTENCY OF COMPOUNDS REQUIRING METABOLIC ACTIVATION
    Stefan Pfuhler (Abstract ID: 1090)
  • P577: HIGH-THROUGHPUT SCREENING TO PREDICT HERG INHIBITION
    Nicole Kleinstreuer (Abstract ID: 1095)
  • P578: SYSTEMATIC EVIDENCE MAPPING OF RESEARCH ON ENVIRONMENTAL EXPOSURES AND CARDIOVASCULAR DISEASE
    Nicole Kleinstreuer (Abstract ID: 1096)
  • P579: AN IN VITRO PANEL FOR COSMETIC CHEMICAL SYSTEMIC TOXICITY SAFETY TESTING
    Catherine Mahony (Abstract ID: 1097)
  • P580: THE USE OF IN VITRO 2D CULTURES AND 3D CORNEA-LIKE TISSUE MODELS IN THE SAFETY ASSESSMENT OF OCULAR IRRITATION AND PHOTO-IRRITATION OF MEDICAL DEVICES AND DRUGS
    Helena Kandarova (Abstract ID: 1098)
  • P581: ASSESSMENT OF PHOTOTOXIC POTENTIAL OF CHEMICALS USING THE IN VITRO 3D-PT SKINETHIC RHE TEST METHOD
    Nathalie Alépée (Abstract ID: 1099)
  • P582: RETROSPECTIVE ANALYSIS OF IN VITRO DATA GENERATED IN RECONSTRUCTED 3D SKIN MODELS TO SUPPORT THE DEVELOPMENT OF NEW OECD TEST GUIDELINE FOR PHOTOTOXICITY TESTING
    Helena Kandarova (Abstract ID: 1100)
  • P586: INTERNATIONAL REGULATORY NEEDS FOR ACUTE TOXICITY DATA
    Judy Strickland (Abstract ID: 1108)
  • P588: RECONSTRUCTED HUMAN EPIDERMIS TO PREPARE FOR ANIMAL TEST BAN FOR COSMETICS IN COLOMBIA
    Rodrigo De Vecchi (Abstract ID: 1112)

 

Theme 2: Innovative technologies

  • P1: LINKING LRI AMBIT CHEMOINFORMATIC SYSTEM WITH THE IUCLID6 SUBSTANCE DATABASE TO SUPPORT READ-ACROSS OF SUBSTANCE ENDPOINT DATA AND CATEGORY FORMATION
    Bruno Hubesch (Abstract ID: 14)
  • P2: CLINICAL TRIAL ON TARGETED DELIVERY OF DOXORUBICIN-LOADED COCKLE SHELL-DERIVED NANOPARTICLES ON DOG BEARING SOLID TUMOUR
    Abubakar Danmaigoro (Abstract ID: 26)
  • P4: AN IN VIVO SCREENING DEVICE PLATFORM TO REDUCE ANIMAL EXPERIMENTS
    Lorenzo Moroni (Abstract ID: 36)
  • P9: SKIN-ON-CHIP: SHARING THE EXPERIENCE FROM RESEARCH TO VALIDATION
    Shujun Cheng (Abstract ID: 79)
  • P11: SYSTEMATIC REVIEWS TO REPLACE SPECIFIC ANIMAL EXPERIMENTS FOR ANSWERING BIOLOGICAL QUESTIONS
    Cathalijn Leenaars (Abstract ID: 83)
  • P13: COMPARATIVE APPROACH TO MONITORING RODENT COLONIES FOR INFECTIOUS AGENTS
    Aurore Dodelet-Devillers (Abstract ID: 91)
  • P14: DEVELOPMENT AND USE OF DRUG-INDUCED CHOLESTASIS, CIRRHOSIS, HEPATITIS, AND STEATOSIS PREDICTION MODELS
    Hyun Kil Shin (Abstract ID: 97)
  • P15: CELLASYS #8: A MICROPHYSIOMETRIC ASSAY TO ASSES ENHANCED CELL CULTURE MEDIA
    Joachim Wiest (Abstract ID: 100)
  • P16: INSIGHTS ON P-GLYCOPROTEIN LIGAND INTERACTIONS FROM MOLECULAR DYNAMICS SIMULATIONS
    Liadys Mora Lagares (Abstract ID: 104)
  • P18: IN VITRO SKIN TESTS FOR THE DETECTION OF SENSITIZATION, IMMUNOTOXICITY, AND ASSESSMENT OF RELATIVE POTENCY
    Asif Tulah (Abstract ID: 114)
  • P19: DEVELOPMENT OF A FULL-THICKNESS 3D AUTOLOGOUS SKIN EQUIVALENT MODEL TO DETERMINE IMMUNOGENICITY OF THERAPEUTICS
    Asif Tulah (Abstract ID: 115)
  • P26: A PRECISELY ADJUSTABLE, LIVE ANIMAL FREE OCULAR CORROSION MODEL
    Markus Glaudo (Abstract ID: 125)
  • P27: THE VALIDATION OF A SEMI-HIGH THROUGHPUT AUTOMATED OCULAR TOXICITY TEST
    Markus Glaudo (Abstract ID: 126)
  • P31: A NEW RELIABLE IN SILICO SCREEN FOR ENDOCRINE DISRUPTORS, EFFECTIVELY REDUCING ANIMAL EXPERIMENTATION
    Paul Christopher Thomas (Abstract ID: 133)
  • P33: IN SILICO ASSESSMENT OF ACUTE ORAL TOXICITY FOR MIXTURES
    Yaroslav Chushak (Abstract ID: 145)
  • P35: EARLY-CAREER RESEARCHERS ADVANCING 21ST CENTURY SCIENCE: AN EDUCATIONAL INITIATIVE FOR HUMAN-RELEVANT BIOMEDICAL RESEARCH
    Janine McCarthy (Abstract ID: 147)
  • P39: FUTURE PRE-CLINICAL DRUG TESTING IN GBM; 3D, ALL-HUMAN, MULTIPLE CELL TYPE, IN VITRO SYSTEMS ACCURATELY REFLECT IN SITU BRAIN MICROENVIRONMENT AND CAN ASSESS DIFFERING CYTOTOXIC PATHWAYS.
    Geoffrey John Pilkington (Abstract ID: 154)
  • P40: THREE-STAGE APPROACH FOR EVALUATION OF A CHEMICALLY DEFINED CELL CULTURE MEDIUM FOR THE CACO-2 CELL LINE: SHORT-TERM EFFECTS, DIFFERENTIATION POTENTIAL AND LONG-TERM CULTIVATION
    Joachim Wiest (Abstract ID: 157)
  • P41: EVALUATION OF A NOVEL ORAL MUCOSA IN VITRO IMPLANTATION MODEL FOR ANALYSIS OF MOLECULAR INTERACTIONS WITH DENTAL ABUTMENT SURFACES
    Sue Gibbs (Abstract ID: 158)
  • P46: USING PLATELET-RICH HUMAN PLATELET LYSATE TO SUBSTITUTE FETAL CALF SERUM FOR CULTIVATION OF MESENCHYMAL STROMAL CELLS
    Moritz Pfeiffenberger (Abstract ID: 168)
  • P47: CHEMICALLY DEFINED FORMATION OF SPHEROIDS LOADED WITH SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES
    Joachim Wiest (Abstract ID: 169)
  • P54: IMPLEMENTATION OF COST-EFFECTIVE FORCE SENSORS FOR MECHANICAL LOADING FEEDBACK ON A BONE-ON-A-CHIP.
    Jose Manuel Villarejo Ramos (Abstract ID: 180)
  • P62: NON-ANIMAL EFFICACY TESTING APPROACHES FOR ECTOPARASITICIDES
    Katherine Groff Werchadlo (Abstract ID: 194)
  • P63: USE OF TRANSCRIPTOMICS TO SUBSTANTIATE SIMILAR BIOLOGICAL ACTIVITY IN A READ ACROSS EXERCISE FOR SAFETY ASSESSMENT OF COSMETIC INGREDIENTS.
    Jorge M Naciff (Abstract ID: 197)
  • P64: THREE DIMENSIONAL NUCLEUS IMAGING ANALYSIS & IN VITRO GENOTOXICITY TEST THROUGH ADVANCED CYTOKINESIS-BLOCK MICRONUCLEUS ASSAY
    SunHyun Park (Abstract ID: 198)
  • P72: OPTIMIZATION OF GENE SILENCING IN A CELL-LADEN 3D ORGAN-LIKE MODEL BY MEANS OF RNA INTERFERENCE
    Ida Shaef (Abstract ID: 211)
  • P74: TRANSCRIPTOME ANALYSIS OF LONG NONCODING RNAS REVEALS THEIR POTENTIAL ROLES IN ANTHRACYCLINE INDUCED CARDIOTOXICITY
    Nhan Nguyen (Abstract ID: 215)
  • P79: RETHINK3R - DESIGN THINKING WORKSHOPS TOWARDS THE IMPLEMENTATION OF THE 3RS
    Annemarie Lang (Abstract ID: 220)
  • P86: THE CELLULAR MECHANISMS OF SKIN IRRITATION THROUGH TRP CHANNELS ACTIVATION
    Maori Kono (Abstract ID: 233)
  • P87: POPULATION EFFECT ON DRUG METABOLISM AND ABSORPTION USING EX VIVO INTESTINAL TISSUE EXPLANTS IN THE INTESTINE EXPLANT BARRIER CHIP
    Evita van de Steeg (Abstract ID: 239)
  • P89: KIDNEY-ON-A-CHIP – INTEGRATING GLOMERULAR FILTRATION AND TUBULAR REABSORPTION MODELS
    Michelle Jäschke (Abstract ID: 241)
  • P93: NUTRITIONAL REQUIREMENTS OF FISH CELL LINES –DEVELOPMENTS TOWARDS A SERUM-FREE CULTURE MEDIUM
    Barbara Jozef (Abstract ID: 249)
  • P101: ENGINEERING A PHYSIOLOGICALLY RELEVANT 3D VILLI-SHAPED INTESTINAL TISSUE
    Joana Costa (Abstract ID: 265)
  • P104: DEVELOPMENT OF A DIET-INDUCED MODEL FOR NON-ALCOHOLIC STEATOHEPATITIS (NASH) AND FIBROSIS IN A TRIPLE CELL-TYPE, SPHEROID-BASED LIVER-ON-CHIP MODEL WITH MICROFLUIDICS
    Geurt Stokman (Abstract ID: 271)
  • P110: DEVELOPMENT OF AN IN VITRO B CELL ASSAY FOR TETANUS AND DIPHTHERIA CONTAINING VACCINE BATCH TESTING USING ANTIGEN SPECIFIC B CELLS FROM HEALTHY DONORS
    Olga Ticha (Abstract ID: 282)
  • P113: A DIGITAL TOOL BASED ON TRANSCRIPTOMIC DATA FOR THE INTEGRATION OF BIOLOGICAL FINGERPRINT ANALOGIES IN THE READ-ACROSS APPROACH
    Anne Riu (Abstract ID: 291)
  • P114: IN SILICO MODELLING OF TUBERCULOSIS IN A COMPUTATIONAL LUNG OF MINIPIG
    Martí Català (Abstract ID: 294)
  • P118: 3D HUMAN TISSUES WITHIN THE MIVO-MULTI IN VITRO ORGAN FLUIDIC DEVICE FOR IMPROVING THE OUTCOME OF IN VITRO DRUG TESTING ASSAYS
    silvia scaglione (Abstract ID: 299)
  • P119: ANIMAL MODELS USED FOR REGENERATIVE MEDICINE RESEARCH IN COSTA RICA. A CASE OF STUDY: SKIN WOUND HEALING.
    Johan Enrique Morales-Sánchez (Abstract ID: 304)
  • P122: CURRENT STATUS OF THE RE-PLACE DATABASE COMPRISING EXPERTISE ON THE USE OF NAMS IN BELGIUM
    Mieke Van Mulders (Abstract ID: 308)
  • P125: ASSESSING REPRODUCIBILITY, ROBUSTNESS AND PREDICTIVITY OF AN IN VITRO METHOD TO ASSESS DIO1 INHIBITION IN HUMAN LIVER MICROSOMES
    Andreas Georg Weber (Abstract ID: 313)
  • P126: MINIATURIZING OF LIVER METABOLOMICS IN VITRO – A NEW SCREENING APPROACH TO GENERATE METABOLIC FINGERPRINT IN HEPG2 CELLS
    Barbara Birk (Abstract ID: 314)
  • P134: DEVELOPMENT OF A GUT-ON-A-CHIP DEVICE TO DUALLY PERFUSE HUMAN TISSUE BIOPSIES.
    Miriam Graute (Abstract ID: 325)
  • P139: DEVELOPMENT OF AN OPTIMIZED CULTURE MEDIUM TO DIFFERENTIATE MUTZ-3 CELLS INTO MUTZ-LANGERHANS CELLS FOR IN VITRO SKIN SENSITIZATION ASSAYS
    Patricia Böttcher (Abstract ID: 333)
  • P145: LONG TERM CULTURE FOR REPEATED DOSE ASSAY : ARE 3D MODELS RELEVANT ?
    Christelle Videau (Abstract ID: 345)
  • P152: A MICROFLUIDIC THYROID-LIVER PLATFORM TO INVESTIGATE MECHANISMS OF THYROID TOXICITY IN HUMANS AND RATS
    Marian Raschke (Abstract ID: 362)
  • P167: BASIC STUDIES OF CYTOTOXICITY ASSAY BY USING CULTURED PLANT CELLS
    Risa Homma (Abstract ID: 387)
  • P168: DEVELOPMENT OF IN VITRO IMMUNOCOMPETENT HUMAN AIRWAY EPITHELIAL MODELS FOR TOXICITY TESTING AND INFECTIOUS DISEASES RESEARCH
    Samuel Constant (Abstract ID: 388)
  • P170: PRIMARY HUMAN 3D AIRWAY-MACROPHAGE CULTURE PLATFORM TO ASSESS TOXICITY OF SUSPENDED VS AEROSOLIZED ZNO NANOPARTICLES
    Samuel Constant (Abstract ID: 391)
  • P171: CILIOPATHIC AND INFLAMMATORY EFFECT OF POLY(I:C) ON IN VITRO 3D HUMAN AIRWAY EPITHELIUM
    Samuel Constant (Abstract ID: 392)
  • P176: CHEMICALLY DEFINED CELL CULTURE MEDIA – A CONTRIBUTION TO ADDRESS THE REPRODUCIBILITY CRISIS IN BIOMEDICAL SCIENCES
    Joachim Wiest (Abstract ID: 397)
  • P177: REAL LIFE APPLICATION OF PROPOSED GUIDELINES FOR HIPSC BANKING IN AN ACADEMIC ENVIRONMENT
    Julia Tigges (Abstract ID: 398)
  • P179: THE HUMAN INDUCED PLURIPOTENT STEM CELL (HIPSC) TEST AS AN ALTERNATIVE METHOD FOR DEVELOPMENTAL TOXICITY TESTING
    Saskia Galanjuk (Abstract ID: 401)
  • P180: OPTIMIZING THE GENERATION OF HUMAN INDUCED NEURAL PROGENITOR CELL (HINPC)-DERIVED FUNCTIONAL NEURONAL NETWORKS FOR USE AS ALTERNATIVE MODELS IN NEUROTOXICITY TESTING
    Julia Hartmann (Abstract ID: 402)
  • P185: MATURATION OF HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES BY MECHANICAL STIMULUS
    Hyang-Ae Lee (Abstract ID: 410)
  • P188: WHOLE ORGAN CULTURES AS ADVANCED MODELS TO ASSESS STEM CELL REGENERATIVE POTENTIAL IN DEGENERATIVE DISC DISEASE
    Marianna Peroglio (Abstract ID: 415)
  • P190: SELF-ORGANIZED PIGMENTED AND VASCULARIZED FULL SKIN TISSUE MODEL FOR MELANOMA RESEARCH
    Alexandra P. Marques (Abstract ID: 418)
  • P191: DIFFERENTIATION OF MOTOR NEURONS FOR IN VITRO POTENCY ESTIMATION OF BOTULINUM NEUROTOXINS
    Maren Schenke (Abstract ID: 419)
  • P210: THE CARDIAC EMBRYONIC STEM CELL TEST SHOWS PRESENCE OF BIOMARKERS FOR ENDODERMAL, ECTODERMAL, AND NEURAL DIFFERENTIATION
    Gina Mennen (Abstract ID: 450)
  • P217: TARGETED WHOLE TRANSCRIPTOME GENE EXPRESSION PROFILING REVEALS COMPARABLE RESPONSE TO FENOFIBRATE IN VITRO AND IN VIVO
    Chiara Herzog (Abstract ID: 461)
  • P218: LONG-READ RNA SEQUENCING FOR DRUG TOXICITY PREDICTION
    Ralf Herwig (Abstract ID: 465)
  • P219: INTESTINAL MUCUS AND THE AMPS REG3B AND REG3G ARE REGULATED BY DC-DERIVED IL6 AND TNF AND T CELL-DERIVED IL22
    Saertje Verkoeijen (Abstract ID: 467)
  • P220: ALTERNATIVE METHOD TO CULTURE INTESTINAL ORGANOIDS WITHOUT LOSS OF BIOLOGICAL FUNCTIONALITY
    Kitty van Summeren (Abstract ID: 468)
  • P221: ORGAN-ON-A-CHIP: 3D HUMAN INTESTINAL MODELS SUITABLE FOR HIGH THROUGHPUT SCREENING
    Elvira van der Vijver (Abstract ID: 469)
  • P226: THE ORGANOTEER : A SENSITIVE TEER MEASUREMENT PLATFORM FOR HIGH THROUGHPUT SCREENING OF ORGANS-ON-CHIPS
    Elvira van der Vijver (Abstract ID: 475)
  • P227: MASS SPECTROMETRY-BASED QUANTIFICATION OF ALL ANTIGENS IN DIPHTHERIA-TETANUS-ACELLULAR PERTUSSIS COMBINATION VACCINES CONTAINING ALUMINUM HYDROXIDE AS ADJUVANT
    Larissa van der Maas (Abstract ID: 476)
  • P228: COMBINATORIAL MODEL ORGANISM STRATEGY TO PREDICT DEVELOPMENTAL AND REPRODUCTIVE TOXICITY (DART)
    Johanna Louter - van de Haar (Abstract ID: 477)
  • P229: ULTRASTRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A RECONSTRUCTED HUMAN CORNEAL EPITHELIUM (HCE) AS AN ALTERNATIVE TO ANIMAL USE
    Christian Pellevoisin (Abstract ID: 478)
  • P230: MIXTURE-BASED QSAR MODELS OF OCULAR TOXICITY FOR REGULATORY HAZARD CATEGORIES
    Neepa Choksi (Abstract ID: 479)
  • P233: WHOLE BLOOD THROMBIN GENERATION TEST TO REDUCE ANIMALS USED FOR PLASMA COLLECTION AND SINGLE DOSE STUDIES
    Maria Kiersgaard (Abstract ID: 483)
  • P239: FULLY HUMAN SKIN-ON-A-CHIP WITH A MODULAR ARCHITECTURE AND INTEGRATED SENSORS FOR DRUG SCREENING AND DISEASE MODELLING
    Patricia Zoio (Abstract ID: 497)
  • P244: LC-MS-BASED EVALUATION OF PROTEIN STRUCTURE OF HEAT-TREATED TETANUS TOXOIDS
    Thomas Michiels (Abstract ID: 507)
  • P246: CHEMICALLY-SELECTIVE AND LABEL-FREE CHARCATERISATION OF PANCREAS ORGANOIDS INSIDE HYDROGEL MATRICES
    Nathalie Jung (Abstract ID: 511)
  • P250: CELL VIABILITY ASSESSMENT OF CAFFEINE AND VEGETAL BLEND USING SPHEROIDS FORMED BY ADIPOCYTES AND ENDOTHELIAL CO-CULTURE CELL: A HUMAN AND ANIMAL CELLS COMPARISON
    Patricia Santos Lopes (Abstract ID: 519)
  • P253: EVALUATION OF A HUMAN IPSC-DERIVED BBB MODEL FOR REPEATED DOSE TOXICITY TESTING WITH CYCLOSPORINE A AS MODEL COMPOUND
    Sara Wellens (Abstract ID: 523)
  • P257: MICROFLUIDIC PLATFORM FOR DEVELOPMENT OF BIO-ARTIFICIAL RETINA
    Devashree Jahagirdar (Abstract ID: 529)
  • P269: A NOVEL SYSTEM OF INFUSION TO PROVIDE DRUGS WITHIN EX VIVO SKIN MODELS
    Anna Trevisiol (Abstract ID: 547)
  • P273: NEW METHODOLOGY IMPLEMENTATION FOR IN VITRO MICRONUCLEUS ANALYSIS IN A CRO (BIOAGRI LABORATÓRIO LTDA - MERIEUX NUTRISCIENCES): COMPARISON OF CONVENTIONAL MICROSCOPY AND FLOW CYTOMETRY
    Juliana Falcato Vecina (Abstract ID: 553)
  • P286: EVALUATION OF SKIN BARRIER PROPERTIES OF COSMETIC INGREDIENTS USING RECONSTRUCTED HUMAN EPIDERMAL MODEL
    Seolyeong Kim (Abstract ID: 568)
  • P287: THE ESTIMATION OF WHITENING EFFICACY OF COSMETIC INGREDIENTS USING THREE-DIMENSIONAL HUMAN PIGMENTED SKIN MODEL
    Hye Soo Kim (Abstract ID: 570)
  • P289: A FULL THICKNESS LONG TERM SKIN EQUIVALENT ALLOWS REPEATED TESTING OF COSMETICS TO EVALUATE EFFICACY AND SAFETY
    Md Zobaer Hasan (Abstract ID: 572)
  • P294: INVESTIGATING THE EPITHELIAL BARRIER IN HUMAN SKIN 3D TISSUE MODELS WITH A NON-INVASIVE FLUORESCEIN LEAKAGE ASSAY
    Eve Gerecke (Abstract ID: 583)
  • P295: NEW INSIGHT INTO THE MECHANISMS UNDERLYING 5-FLUOROURACIL-INDUCED INTESTINAL TOXICITY BY ESTABLISHING TRANSCRIPTOMIC RESPONSES IN EXPOSED HUMAN INTESTINAL ORGANOIDS
    Daniela Rodrigues (Abstract ID: 584)
  • P296: IN VITRO ORGAN-ON-CHIP MODELS TO PREDICT INTESTINAL DRUG ABSORPTION AND METABOLISM.
    Alysha Bray (Abstract ID: 585)
  • P299: A MATHEMATICAL MODEL FOR ESTIMATING THE DISSOLUTION RATE OF SYNTHETIC VITREOUS FIBERS FROM IN-VIVO STUDIES
    john w hoffman (Abstract ID: 590)
  • P300: REPRODUCING THE SYNOVIAL LINING RESPONSE TO MECHANICAL STIMULATION USING A MULTI-MODAL STIMULATION PATTERN APPROACH
    carlo alberto paggi (Abstract ID: 595)
  • P301: AVATARS OF ANIMALS AND HUMANS: 3D INTERACTIVE HOLOGRAPHIC MODELS.
    Bo van Leeuwen (Abstract ID: 597)
  • P306: ENGINEERING 3D VASCULARIZED HEART TISSUES USING HPSC DERIVED CARDIAC CELLS
    José Manuel Rivera-Arbelaez (Abstract ID: 609)
  • P308: A NOVEL IN SILICO FRAMEWORK FOR IN VITRO MODEL OPTIMIZATION THROUGH GENERALIZED ALLOMETRIC SCALING
    Ermes Botte (Abstract ID: 612)
  • P309: EX VIVO MODEL TO STUDY DYNAMIC INTESTINAL EPITHELIUM RESPONSES TO ENTEROBACTERIA INVASION
    Pilar Samperio Ventayol (Abstract ID: 613)
  • P311: APPLICATION OF HUMAN EMBRYONIC STEM CELLS DERIVED HEPATIC ORGANOIDS TO PREDICT HEPATOTOXICITY IN VITRO
    Wei Cheng (Abstract ID: 616)
  • P312: SUITABILITY AND PERFORMANCE OF BIOOCULLAR AND EPIKUTIS IN VITRO 3D TISSUE MODELS IN CHINA
    Cristi Gomez (Abstract ID: 617)
  • P315: A NOVEL HUMAN MATERIAL-BASED PLATFORM TECHNOLOGY FOR TISSUE ENGINEERING
    Johannes Hackethal (Abstract ID: 625)
  • P318: FDA'S ALTERNATIVE METHODS WORKING GROUP (AMWG) EVALUATING MICROPHYSIOLOGICAL SYSTEMS FOR REGULATORY USE
    Thomas Joseph Maruna (Abstract ID: 631)
  • P321: IMMUNOLOGICAL ISOLATION AND CHARACTERISATION OF NEURONAL PROGENITORS FROM HUMAN DENTAL PULP CELLS.
    Hayley Philomena McMillan (Abstract ID: 635)
  • P322: SENSIBILIZATION TEST IN HACAT CELLS AN IN VITRO AND IN VITRO APPROACH
    Gabriela Gomes Pessoa Glinglani (Abstract ID: 638)
  • P325: ALTERNATIVE TOXICITY TESTING STRATEGIES TO ADVANCE THE 3RS - A CASE STUDY ON CONSERVED MOLECULAR PATHWAYS -
    Diksha Bhalla (Abstract ID: 642)
  • P332: DRUGS AND MUCUS: DECIPHERING THE INTERACTION MECHANISMS USING A BIOSIMILAR MUCUS MODEL
    Cosmin Stefan Butnarasu (Abstract ID: 653)
  • P334: SECONDARY PHARMACOLOGY SCREENING IN PHARMACEUTICAL R&D: A PRELIMINARY SURVEY ANALYSIS OF CURRENT PRACTICES AND EXPERIENCES ACROSS 18 COMPANIES
    Jean-Pierre Valentin (Abstract ID: 657)
  • P335: BETTER THAN MATRIGEL? ALTERNATIVE CELL CULTURE COATINGS FOR INDUCED PLURIPOTENT STEM CELL CULTURE AND RENAL PODOCYTE DIFFERENTIATION
    Anja Wilmes (Abstract ID: 660)
  • P338: A MICRO-CT STUDY OF MICROSTRUCTURE CHANGE OF ALVEOLAR BONE DURING ORTHODONTIC TOOTH MOVEMENT IN RATS
    Simone Friedrichsdorf (Abstract ID: 665)
  • P339: THE USE OF ANIMAL-DERIVED PRODUCTS IN IN VITRO METHODS FOR SKIN SENSITIZATION TESTING
    Bianca Marigliani (Abstract ID: 666)
  • P346: 3D IN VITRO TISSUE MODELS: ETHICAL, ECONOMICAL, EFFICIENT AND HUMAN RELEVANT ALTERNATIVES TO ANIMAL RESEARCH AND THEIR POTENTIAL TO ELUCIDATE HUMAN MALE-FEMALE DIFFERENCES IN PHYSIOLOGY AND DISEASE PATTERNS
    Sushila Maharjan (Abstract ID: 682)
  • P347: A DYNAMIC PERFUSION BASED BLOOD- BRAIN BARRIER MODEL FOR CYTOTOXICITY TESTING AND DRUG PERMEATION
    Basma el Bakary (Abstract ID: 687)
  • P353: USE OF THE FULL THICKNESS MODEL, T-SKIN™, TO INVESTIGATE THE EFFECTS OF UVA AND UVB ON SKIN AND PHOTOPROTECTIVE EFFECTS OF VITAMIN C
    Christian Pellevoisin (Abstract ID: 701)
  • P354: MAKE PEOPLE BETTER SCIENTISTS IN THE LAB: ALTERTOX VISION.
    Valentin Salamone (Abstract ID: 702)
  • P355: IN VITRO HUMAN GINGIVAL FIBROBLASTS CULTIVATION WITH HUMANIZED CULTURE MEDIUM ON THE PRF MEMBRANES FOR ORAL SURGERIES REHABILITATION
    Mª Fátima Guarizo Klingbeil (Abstract ID: 704)
  • P356: REMODEL - RESEARCH MODELS IN INFECTION, CANCER, AND TISSUE REGENERATION: REPLACEMENT AND TRANSLATION
    Marta Luisa Sousa Dias Alves da Silva (Abstract ID: 707)
  • P357: EXTENSIONS OF THE TOXTRACKER ASSAY FOR MECHANISTIC INSIGHT INTO THE MODE OF ACTION OF GENOTOXIC COMPOUNDS
    Giel Hendriks (Abstract ID: 708)
  • P361: CREATING TARGET IMAGES ON ANIMAL-FREE RESEARCH.
    Elmar Petra Theune (Abstract ID: 715)
  • P362: INTEGRATION OF EXTRACELLULAR METABOLOMICS AND INTRACELLULAR TRANSCRIPTOMICS TO UNRAVEL THE MECHANISMS OF 5-FU-INDUCED GASTROINTESTINAL TOXICITY
    Terezinha Souza (Abstract ID: 719)
  • P365: IMPEDANCE SPECTROSCOPY CONTROLLED PLACENTA-ON-CHIP MODEL FOR ANALYSIS OF DRUG TRANSPORT AND TOXICITY
    Evgeny Knyazev (Abstract ID: 725)
  • P369: COMPARING TOXICANT-INDUCED TRANSCRIPTOMIC RESPONSES IN IPSC AND CD34+ HEMOPOIETIC STEM CELL DERIVED MACROPHAGES AND DENDRITIC CELL MODELS USING TEMPO-SEQ
    Leonie Fransen (Abstract ID: 734)
  • P376: REPROTRACKER: A HUMAN STEM CELL-BASED BIOMARKER ASSAY FOR IN VITRO ASSESSMENT OF DEVELOPMENTAL TOXICITY
    Myrto Dimopoulou (Abstract ID: 743)
  • P380: 50 YEARS OF ANIMAL FREE RESEARCH FUNDING
    Alpesh Patel (Abstract ID: 750)
  • P381: AN ORGANOTYPIC MODEL OF SMALL INTESTINE WITH INCORPORATED MACROPHAGES – NOVEL TOOL FOR MODELING GUT INFLAMMATION
    Jan Markus (Abstract ID: 751)
  • P382: DATA-DRIVEN KINETIC MODELING OF P53 SIGNALING LINKED TO CELL CYCLE PROGRESSION
    Muriel Heldring (Abstract ID: 752)
  • P383: IN VITRO MODELING OF GASTROINTESTINAL EXPOSURE AND RESPONSE TO ENGINEERED NANOMATERIALS
    Marek Puskar (Abstract ID: 753)
  • P385: THERMOPLASTIC POLYURETHANE FILMS AS BIOMATERIAL - PHYSICAL-CHEMICAL AND BIOLOGICAL STUDY OF THE MODIFICATION CAUSED BY IONIZING RADIATION
    Mariana Gurgel Rodrigues Massei (Abstract ID: 756)
  • P391: A NOVEL IN SILICO TOOL FOR DOSE ASSESSMENT IN CELL MONOLAYER NANOTOXICOLOGY
    Ermes Botte (Abstract ID: 765)
  • P395: SYSTEMATIC ANALYSIS OF MITOCHONDRIAL PERTURBATION IN CHEMICAL-INDUCED ORGAN TOXICITY USING HIGH-CONTENT IMAGING AND HIGH-THROUGHPUT TRANSCRIPTOMICS
    Martijn J Moné (Abstract ID: 774)
  • P396: SUBACUTE 28-DAY RESPIRATORY TOXICITY ASSAY USING AN IN VITRO HUMAN AIRWAY MODEL
    Jan Markus (Abstract ID: 775)
  • P398: TRANSCRIPTOMIC ALTERATIONS IN HUMAN IPSC DERIVED PODOCYTES EXPOSED TO DOXORUBICIN, PAMIDRONATE AND CYCLOSPORINE A.
    Cormac Murphy (Abstract ID: 777)
  • P399: DEVELOPMENT OF A HYBRID PROGNOSTIC SIGNATURE OF HEAD AND NECK CANCER PROGRESSION USING MACHINE LEARNING APPROACHES
    Gehad Youssef (Abstract ID: 778)
  • P400: DISSEMINATING CELLS IN HUMAN TUMOURS ACQUIRE AN EMT STEM CELL STATE THAT IS PREDICTIVE OF METASTASIS
    Gehad Youssef (Abstract ID: 779)
  • P401: EVALUATION OF THE SINGLE-CELL LEVEL IMMUNO-EFFICACY OF RECOMBINANT PROTEIN FOR AVIAN INFLUENZA SUBUNIT VACCINES WITH AN NOVEL AAT INTEGRATION PLATFORM
    Jie-Long He (Abstract ID: 782)
  • P402: EMULATING THE GUT-LIVER AXIS: DISSECTING THE MICROBIOME’S EFFECT ON DRUG METABOLISM USING MULTI-ORGAN-ON-CHIP MODELS
    Mara Lucchetti (Abstract ID: 784)
  • P403: AUTOMATED FEATURE RECOGNITION IN ZEBRAFISH EMBRYOS FOR DEVELOPMENTAL TOXICITY TESTING
    Stefan Scholz (Abstract ID: 786)
  • P404: AUTOMATED TOPOLOGY BUILDER: THE BUILDING BLOCKS FOR COMPUTATIONAL DRUG DESIGN
    Nicole C Wheatley (Abstract ID: 789)
  • P406: APPLICATION OF IMPEDANCE SPECTROSCOPY FOR ANALYSIS OF THE INTESTINE-ON-CHIP MODEL BASED ON CACO-2 CELLS
    Sergey Nikulin (Abstract ID: 792)
  • P411: IN VITRO SKIN IRRITATION PROTOCOL FOR THE MEDICAL DEVICES EXTRACTS USING EPIDERM MODEL
    Silvia Letasiova (Abstract ID: 799)
  • P417: HIPSC FLUORESCENT PROTEIN REPORTER LINES FOR DISSECTING LINEAGE-SPECIFIC CELLULAR STRESS RESPONSE DYNAMICS USING HIGH CONTENT IMAGING
    Kirsten Snijders (Abstract ID: 805)
  • P418: PHYSIOLOGICALLY RELEVANT TRANSWELL CULTURES OF HUMAN CELLS TO ASSESS EFFECTS OF CYANOBACTERIAL LIPOPOLYSACCHARIDES
    Petra Laboha (Abstract ID: 806)
  • P419: LIVER SPHEROID CO-CULTURES WITH FRESH OR CRYOPRESERVED HEPATOCYTES AND ENDOTHELIAL CELLS AS TOOL TO INVESTIGATE METABOLISM AND HEPATOTOXICITY
    Anett Ullrich (Abstract ID: 811)
  • P420: A NOVEL POLYMER GENERATES CELL REPELLENT SURFACES AND ALLOWS 3D CELL CULTURE
    Anett Ullrich (Abstract ID: 814)
  • P421: HEPATIC NON-PARENCHYMAL CELLS ISOLATED FROM RODENT LIVERS AND CHARACTERIZED FOR THE DEVELOPMENT OF PRIMARY HEPATIC CO-CULTURES
    Anett Ullrich (Abstract ID: 816)
  • P422: IMPACT OF CULTURE CONDITIONS ON THE EXPRESSION AND FUNCTION OF BILE ACID TRANSPORTERS IN PRIMARY RAT HEPATOCYTES
    Anett Ullrich (Abstract ID: 818)
  • P425: THREE-DIMENSIONAL CULTURE IMPROVES THE MORPHOLOGY AND FUNCTION OF CARDIOMYOCYTES DERIVED FROM HUMAN PLURIPOTENT STEM CELLS
    Hyang-Ae Lee (Abstract ID: 828)
  • P427: CHARACTERIZATION OF CHEMICAL MECHANISMS-OF-ACTION BY TRANSCRIPTIONAL NETWORK ANALYSIS AND 3D VISUALIZATION: PERFLUOROOCTANOIC ACID EXPOSURE IN RAT LIVER AS A CASE STUDY
    Ruchir R Shah (Abstract ID: 835)
  • P428: FUTURE PERSPECTIVES FOR SKIN MICROFLUIDICS SYSTEMS USING GRAPHENE-BASED BIOSENSORS
    Fabiana Medeiros (Abstract ID: 836)
  • P429: SAAGAR – NEW SET OF CHEMICAL FEATURES FOR INTERPRETABLE QSAR/QSPR AND READ-ACROSS PREDICTIONS
    Ruchir R Shah (Abstract ID: 838)
  • P430: SUCCESSFUL DEVELOPMENT OF RECOMBINANT HUMAN DIPHTHERIA ANTITOXIN: A PROJECT UPDATE
    Jeffrey Brown (Abstract ID: 839)
  • P431: ADVANCING EXTRACELLULAR VESICLES TOWARDS MAINSTREAM MEDICINE FOR ACUTE AND CHRONIC LUNG INJURIES USING HUMAN PHYSIOLOGY-MIMICKING LUNG MODELS.
    Wojtek Chrzanowski (Abstract ID: 840)
  • P434: IMAGING-BASED SINGLE CELL DYNAMICS OF KEAP1/NRF2 PATHWAY ACTIVATION STATUS TO QUANTIFY PRO-OXIDANT-INDUCED CELL FATE DECISIONS.
    Johannes Schimming (Abstract ID: 845)
  • P436: DIFFERENTIATION AND UPREGULATION OF SPECIALIZED EPITHELIAL CELLS IN PORCINE AND HUMAN INTESTINAL ORGANOIDS
    Judith Lehmann (Abstract ID: 865)
  • P445: DEVELOPMENT OF A NEW PERFUSION SYSTEM ON HUMAN IN VITRO BLOOD-BRAIN BARRIER BIOCHIP FOR TOXICITY ASSESSMENT
    Adrien Roux (Abstract ID: 888)
  • P446: INCREASING THE PHYSIOLOGICAL RELEVANCE OF THE GUT-ON-CHIP MODEL
    Mathilda Kaminska (Abstract ID: 903)
  • P448: AN ADVANCED PLURIPOTENT STEM CELL TEST FOR DEVELOPMENTAL TOXICITY
    Karin Lauschke (Abstract ID: 913)
  • P449: EVALUATING DRUG-INDUCED LIVER TOXICITY OF ACETAMINOPHEN, TROVAFLOXACIN AND LEVOFLOXACIN IN A TRIPLE-CELL MICROPHYSIOLOGICAL LIVER SINUSOIDAL MODEL
    Tim Kaden (Abstract ID: 921)
  • P455: EXPANSION AND DIFFERENTIATION OF HUMAN LIVER ORGANOIDS IN A NOVEL SYNTHETIC HYDROGEL
    Kerstin Schneeberger (Abstract ID: 927)
  • P458: AUTOMATED TOPOLOGY BUILDER: MAKING MOLECULAR SIMULATIONS BETTER, WORKING TOWARDS REPLACING ANIMAL MODELS.
    Nicole C Wheatley (Abstract ID: 930)
  • P460: USE OF FRIBROBLAST PRIMARY CELL CULTURE TO STUDY PHOTOBIOMODULATION IN HORSES
    Gustavo Marques Araujo (Abstract ID: 933)
  • P461: CAT SKIN CANCER COULD BE A MODEL TO STUDY PHOTODYNAMIC THERAPY?
    Gustavo Marques Araujo (Abstract ID: 934)
  • P463: EFFECTS OF BISPHENOL COMPOUNDS ON THE GROWTH OF MCF-7 HUMAN BREAST CANCER CELLS
    Marina Vasilyeva (Abstract ID: 942)
  • P465: HIGH FREQUENCY APPLICATION OF CATIONIC AGENTS CONTAINING LUBRICANT EYE DROPS CAUSE CUMULATIVE CORNEAL TOXICITY IN AN EX-VIVO (EVEIT) MODEL
    R Michael Dutescu (Abstract ID: 954)
  • P468: PROOF-OF-PRINCIPLE FOR IMPEDANCE MEASUREMENT WITH CARBON ELECTRODES FOR IMPLEMENTATION IN A BONE-ON-A-CHIP SYSTEM
    Joachim Wiest (Abstract ID: 957)
  • P470: NEW INSIGHTS ON ALTERNATIVES IN MEDICINAL MUSHROOM RESEARCH: IN SILICO PREDICTIVE EVALUATION OF EPIGENETIC MODULATORY EVENTS AND ANTI-INFLAMMATORY POTENTIAL OF POLYPHENOLS
    Humberto Morris (Abstract ID: 960)
  • P472: EDUCATORS’ VIEWS ON DISSECTION ALTERNATIVES AT THE ONSET OF THE COVID-19 PANDEMIC
    Pamela Osenkowski (Abstract ID: 962)
  • P473: DEVELOPMENT AND CHARACTERIZATION OF THE SKIN SURFACE TEMPERATURE MODULATION AND CONTROL (SKIN-TEMP-MC) DEVICE
    Udo Bock (Abstract ID: 963)
  • P477: AN ORGANOTYPIC RECONSTRUCTED ORAL MUCOSA MODEL ENABLING THE STUDY OF HOST-MICROBIOME REACTIONS SHOWS MULTI-SPECIES BIOFILM PROMOTES HUMAN GINGIVA EPITHELIAL BARRIER FUNCTION
    Lin Shang (Abstract ID: 967)
  • P480: PHARMACOKINETIC FUNCTIONS OF HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED SMALL INTESTINAL EPITHELIAL CELLS
    Shinji Mima (Abstract ID: 970)
  • P482: CYTOTOXICITY OF REFERENCE ELECTRODES IN MICROPHYSIOMETRIC SYSTEMS REVISITED
    Joachim Wiest (Abstract ID: 973)
  • P483: THE E-MORPH ASSAY: SCREENING FOR ANTI-/ESTROGENIC SUBSTANCES BASED ON QUANTITATIVE CHANGES IN CELL-CELL CONTACT ORGANIZATION OF BREAST CANCER CELLS
    Sebastian Dunst (Abstract ID: 974)
  • P484: COMPARATIVE ASSESSMENT OF THE XENOBIOTIC METABOLISM OF LIVER SPHEROIDS CONNECTED IN A CHIP TO HUMAN BRONCHIAL EPITHELIAL 3D TISSUE EXPOSED DIRECTLY TO CIGARETTE SMOKE OR HEATED TOBACCO PRODUCT AEROSOL: EXAMPLE OF A NEW IN VITRO MODEL FOR AEROSOL TES
    David Bovard (Abstract ID: 975)
  • P487: AN IN-VITRO MODEL OF ALVEOLAR INFLAMMATION ON A BREATHING LUNG-ON-CHIP
    Clémentine Richter (Abstract ID: 979)
  • P490: NOVEL FAST COLD FLUSHING CANNULATION FOR TRANSPLANT ORGAN PROCUREMENT
    Yigang Luo (Abstract ID: 984)
  • P499: NON-ANIMAL DERIVED ANTIBODIES IN RESEARCH AND DIAGNOSTICS
    Esther Wenzel (Abstract ID: 994)
  • P500: GENERATION OF REPORTER-GENE MODELS BASED ON GENETICALLY ENGINEERED PROGENITOR CELLS USING CRISPR-CAS9 TECHNOLOGY
    Marion Alriquet (Abstract ID: 995)
  • P501: RECONSTRUCTION OF HEPATIC SINUSOIDAL ZONATION BY ORGAN-ON-A-CHIP FROM MICRONIT
    Seiichi Ishida (Abstract ID: 996)
  • P503: RESPONSE TO RECOMMENDATION ON NON-ANIMAL-DERIVED ANTIBODIES
    Becky Catrin Jones (Abstract ID: 998)
  • P508: OPERA, AN OPEN-SOURCE AND OPEN-DATA SUITE OF QSAR MODELS
    Kamel Mansouri (Abstract ID: 1004)
  • P513: EFFECTIVE USER SUPPORT DOCUMENTATION FOR A TOXICOLOGICAL DATA RESOURCE: ICE AS A CASE STUDY
    Catherine Sprankle (Abstract ID: 1010)
  • P516: THE INHIBITION OF ADIPOGENESIS VIA AN IN VITRO ASSAY CAN REDUCE ANIMAL USE BY MORE PRECISELY ESTIMATING THE STARTING DOSE FOR THE ACUTE TOXIC CLASS METHOD
    Alessandra Melo de Aguiar (Abstract ID: 1015)
  • P517: DEVELOPMENT OF 3D CULTURES OF ZEBRAFISH LIVER AND EMBRYO CELL LINES BY HANGING DROP AND ORBITAL SHAKING METHODS
    Daniela Morais Leme (Abstract ID: 1016)
  • P518: PECTIN-BASED 3D PRINTED MODELS FOR NERVOUS TISSUE
    Marta Tunesi (Abstract ID: 1017)
  • P519: TRANSITIONING A549 CELLS TO FBS-FREE MEDIA: PROCESS AND DETERMINING SUCCESS
    Katherine Groff Werchadlo (Abstract ID: 1018)
  • P520: APPLICATION OF META-ANALYSIS TO DERIVATION OF POINTS-OF-DEPARTURE FOR SHORT-TERM INHALATION EXPOSURE LEVELS OF HAZARDOUS CHEMICALS
    Eugene Demchuk (Abstract ID: 1019)
  • P524: SCALABLE PRODUCTION OF BIOENGINEERED HAIR AND FUR PRODUCTS PROTECTED WITH BIOSECURITY TAGGING FOR THERAPEUTIC APPLICATIONS IN HAIR LOSS AND THE PREVENTION OF FUR FARMING
    Henri Kunz (Abstract ID: 1027)
  • P525: TOWARDS A NOVEL ALTERNATIVE TOXICITY MODEL WITH NORMOTHERMICALLY PERFUSED EX VIVO LIVERS BASED ON WHOLE PORCINE SLAUGHTERHOUSE ORGANS
    Alicia Ruppelt (Abstract ID: 1028)
  • P526: EXPLOITING THE USE OF IPSC DERIVED RENAL PROXIMAL TUBULAR LIKE CELLS TO INVESTIGATE MEGALIN MEDIATED AMINOGLYCOSIDES TOXICITY
    Vidya Chandrasekaran (Abstract ID: 1029)
  • P535: GENE NETWORK REGULATIONS SHOW DIFFERENT SIGNATURES FOR MORPHOLINES AND PIPERIDINES IN THE ESTC
    Gina Mennen (Abstract ID: 1042)
  • P537: ECM-BASED IN VITRO 3D-MODELS OF THE LIVER FOR HEPATOTOXICITY TESTING
    Giuseppe Guagliano (Abstract ID: 1044)
  • P545: THE DEVELOPMENT OF AN EX VIVO ORGAN MODEL TO STUDY PROLONGED VIABILITY OF INDIVIDUAL ORGANS AND EVALUATE THE PERINATAL LIFE SUPPORT SYSTEM PROTOTYPE
    Mattia D'Alessi (Abstract ID: 1054)
  • P547: THE PARADOX OF CHONDROCYTES AND CHONDROSARCOMA CELLS: DO THEY BEHAVE SIMILARLY WHEN EXPOSED TO MECHANICAL CUES?
    carlo alberto paggi (Abstract ID: 1056)
  • P550: THE CHICKEN CHORIOALLANTOIC MEMBRANE AS A PRE-SCREENING METHOD FOR MONITORING BIOCOMPATIBILITY OF POROUS BIOPOLYMER SCAFFOLDS
    Zuzana Demcisakova (Abstract ID: 1059)
  • P553: THE 3D NORTIS PARVIVO KIDNEY-ON-CHIP MODEL OFFERS A PHYSIOLOGICALLY RELEVANT PANEL OF MAMMALIAN TISSUES AS ALTERNATIVES FOR ANIMAL USE IN TESTING DRUG SAFETY AND TOXICOLOGY.
    Henning Mann (Abstract ID: 1063)
  • P556: SKIN-ON-CHIP: SHARING THE EXPERIENCE FROM RESEARCH TO VALIDATION
    Shujun Cheng (Abstract ID: 1067)
  • P559: ASSESSMENT CUMULATIVE CHRONIC IRRITATION BY SINGLE ORGAN CHIP OF SKIN
    Tingting Luo (Abstract ID: 1070)
  • P564: SYSTEMS VACCINOLOGY ENABLE TO EVALUATE VACCINE SAFETY AND QUALITY IN VITRO.
    Takuo Mizukami (Abstract ID: 1076)
  • P565: TUMOR-ON-CHIP MODEL TO EVALUATE THE IMPACT OF MECHANICAL CUES ON BREAST TUMOR AGGRESSIVENESS
    carlo alberto paggi (Abstract ID: 1077)
  • P570: A NOVEL ALTERNATIVE TEST PLATFORM FOR REAL-TIME MONITORING OF TEER VALUES IN HUMAN EPITHELIAL TISSUE MODELS
    Gowsinth Gunasingam (Abstract ID: 1082)
  • P571: AN INNOVATIVE APPROACH TO THE RAPID FORMATION OF BLOOD VESSELS NETWORK-ON-CHIP
    Agnieszka Zuchowska (Abstract ID: 1085)
  • P573: CHRONIC CARDIAC CONTRACTILITY ASSESSMENT OF HUMAN IPSC-DERIVED CARDIOMYOCYTES IN A PRO-MATURATION ENVIRONMENT FOR PRECLINICAL CARDIAC SAFETY AND TOXICITY STUDIES
    Bettina Lickiss (Abstract ID: 1088)
  • P576: STANDARDIZING DEVELOPMENTAL TOXICOLOGY STUDY EXTRACTIONS USING AUTOMATED APPLICATION OF ONTOLOGIES
    Caroline Foster (Abstract ID: 1094)
  • P584: ALT4EI: DETERMINATION OF EYE IRRITATING POTENTIAL OF 59 CHEMICALS USING EPIOCULAR™ TIME-TO-TOXICITY NEAT AND DILUTION PROTOCOLS
    Silvia Letasiova (Abstract ID: 1104)
  • P587: COMPARATIVE TOXICOLOGICAL ANALYSIS OF AN IPSC DERIVED AIRWAY EPITHELIUM MODEL WITH A PRIMARY BRONCHIAL AIRWAY EPITHELIUM MODEL AT AN AIR LIQUID INTERFACE USING TEMPOSEQ
    Ivo Djidrovski (Abstract ID: 1111)

 

Theme 3: Ethics, Welfare and Regulation

  • P6: SUCCESSES AND CHALLENGES IN NETWORKING AND PROMOTING 3RS WITHIN ITALIAN UNIVERSITIES. THE CENTRO 3R EXPERIENCE.
    Arti Ahluwalia (Abstract ID: 56)
  • P8: REPEATING PAST MISTAKES: THE BANALITY AND FUTILITY OF NOWADAYS CIGARETTE SMOKE-RELATED ANIMAL EXPERIMENTATION
    Dilyana Filipova (Abstract ID: 61)
  • P10: SYSTEMATIC REVIEWS TO REPLACE ANIMAL EXPERIMENTS FOR OPTIMISING EXPERIMENTAL DESIGN
    Cathalijn Leenaars (Abstract ID: 82)
  • P12: PROMOTING THE REPLACEMENT OF THE 3RS PRINCIPLE: SHORT COURSES
    Pilar Vinardell (Abstract ID: 90)
  • P17: ASIAN ACTIVITIES FOR ALTERNATIVE TO ANIMAL EXPERIMENTS
    Hajime Kojima (Abstract ID: 105)
  • P23: R-ODAF: OMICS DATA ANALYSIS FRAMEWORK FOR REGULATORY APPLICATION
    Florian Caiment (Abstract ID: 120)
  • P34: BIOLOGICAL DATA OF NONHUMAN PRIMATE DURING THE QUARANTINE PERIODS
    Young-Su Yang (Abstract ID: 146)
  • P37: DIFFERENT MOUSE STRAINS – DIFFERENT NESTING MATERIALS. SEARCHING FOR THE PERFECT REFINEMENT IN THE HOUSING OF MICE
    Beate Obermüller (Abstract ID: 149)
  • P38: CUSTOMIZING ANIMAL WELFARE LEGISLATION FOR ANIMALS USED IN XENOTRANSPLANTATION TRIALS AND PRODUCTION IN THE UNITED STATES
    Mimi Lam (Abstract ID: 152)
  • P42: NOVEL HOME CAGE ACTIVITY METRICS FOR POSTOPERATIVE CARE REFINEMENT IN A MOUSE SURGICAL MODEL
    Fabrizio Scorrano (Abstract ID: 159)
  • P44: THE ROLE OF THE ANIMAL WELFARE BODY IN DEVELOPING A FUNCTIONAL AND EFFICIENT CULTURE OF CARE
    Thomas Bertelsen (Abstract ID: 162)
  • P45: REDUCTION OF CONTROLS IN PRECLINICAL CLAMP STUDIES USING A NON-LINEAR MIXED-EFFECTS MODEL
    Thomas Bertelsen (Abstract ID: 165)
  • P48: MODERNIZING BIOMEDICAL RESEARCH AND REGULATORY POLICIES TO ADVANCE HUMAN HEALTH
    Emily R. Trunnell (Abstract ID: 172)
  • P53: 3RS SELF-ASSESSMENT TOOLS TO SUPPORT RESEARCH GROUPS AND INSTITUTIONS TO TRACK, EVALUATE AND BENCHMARK THEIR 3RS ACTIVITIES
    Mark Prescott (Abstract ID: 179)
  • P67: ANIMAL DISSECTION IN TEACHING MINORS (UNDER 19 YEARS OF AGE) IN KOREA - CONTRADICTORY KOREAN LEGISLATION AND ENFORCEMENT RULE
    Gwi Hyang Lee (Abstract ID: 202)
  • P71: A NOVEL METHOD FOR COMPILING U.S. ANIMAL RESEARCH AND TESTING NUMBERS AND THE CASE FOR A NEW GOVERNMENT SYSTEM
    Ryan Merkley (Abstract ID: 210)
  • P83: PREREGISTRATION CAN SUPPORT ANIMAL WELFARE IN BIOMEDICAL SCIENCE
    Bettina Bert (Abstract ID: 226)
  • P84: IMPROVING QUALITY OF IN VITRO METHODS: A GIVIMP CERTIFICATION PROGRAM
    Erin Hill (Abstract ID: 228)
  • P94: ANALYSIS AND REFLECTION ON THE ROLE OF THE 90-DAY ORAL TOXICITY STUDY IN EUROPEAN CHEMICAL RISK ASSESSMENT
    Misha Vrolijk (Abstract ID: 250)
  • P103: DEVELOPMENT OF GUIDANCE FOR IACUC MEMBERS IN KOREA: APPLYING THE 3RS PRINCIPLES
    Gwi Hyang Lee (Abstract ID: 270)
  • P112: IMPROVING ANIMAL RESEARCH: ENHANCING SYSTEMATIC REVIEW METHODOLOGY
    Cathalijn Leenaars (Abstract ID: 288)
  • P117: SMAFIRA: SMART FEATURE BASED INTERACTIVE RANKING TO RETRIEVE POSSIBLE ALTERNATIVES FROM THE LITERATURE
    Daniel Butzke (Abstract ID: 298)
  • P123: TELEMETRY AS METHOD TO ASSESS SEVERITY IN SHEEP
    Christine Häger (Abstract ID: 309)
  • P137: IDENTIFYING FISH - METHODS FOR TAGGING AND MARKING
    Per E Ljung (Abstract ID: 329)
  • P138: THE PROBLEM OF PAIN IN ANIMAL EXPERIMENTATION
    Katherine Virginia Roe (Abstract ID: 330)
  • P143: THE RODENT IN THE ROOM: CONSIDERING SENTIENCE IN RESEARCH PROGRAMS USING MICE AND RATS
    Ingrid Taylor (Abstract ID: 342)
  • P153: A PERFECT MATCH REDUCES ANIMAL USE.
    Ronald Vlasblom (Abstract ID: 364)
  • P160: IMPLEMENTATION OF ALTERNATIVE METHODS IN CHINA ACCORDING TO OECD GUIDANCE DOCUMENT ON GOOD IN VITRO METHOD PRACTICES: AN EXAMPLE
    Nan LI (Abstract ID: 376)
  • P165: DEFINING PHYSICOCHEMICAL EXCLUSION RULES TO IDENTIFY CHEMICALS THAT DO NOT REQUIRE CLASSIFICATION OF SERIOUS EYE DAMAGE/EYE IRRITATION: A COSMETIC EUROPE ANALYSIS
    Arianna Giusti (Abstract ID: 383)
  • P186: PREDICTABILITY OF DORSAL ROOT GANGLION NEURONAL RESPONSE TO HYPOXIC STRESS: A CELL LINE, PRIMARY CELL AND ORGAN MODEL VALIDATION STUDY
    Marianna Peroglio (Abstract ID: 413)
  • P187: FOSTER AND FUND: ENHANCING 3R ACTIVITIES AT CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN BY CHARITÉ 3R
    Ida Retter (Abstract ID: 414)
  • P193: IMPLEMENTING THE PRINCIPLES OF 3R'S IN THE PROJECT APPLICATION, EVALUATION, AND AUTHORIZATION PROCESS IN THE UNIVERSITY OF DEBRECEN COMMITTEE OF ANIMAL WELFARE’S WORK
    Ádám Deák (Abstract ID: 423)
  • P195: MULTIMODAL MONITORING IN A PRECLINICAL STUDY: WHEEL RUNNING BEHAVIOUR UNCOVERS IMPAIRED WELFARE DUE TO SERIAL INTRAPERITONEAL INJECTIONS
    Eva Zentrich (Abstract ID: 425)
  • P196: RECOMMENDATIONS ON GROUP HOUSING OF MALE MICE - A COMPILATION OF EXPERIENCES FROM SWEDISH LABORATORY ANIMAL FACILITIES AND SCIENTIFIC LITERATURE
    Kaisa Askevik (Abstract ID: 427)
  • P204: MARCHING TOWARDS ASIAN FEDERATION FOR ALTERNATIVES TO ANIMAL TESTING (AFAAT) THROUGH HARMONIZATION OF ASIAN 3R CENTRES AND ASSOCIATIONS FOR ALTERNATIVES
    Mangala Gunatilake (Abstract ID: 438)
  • P212: THE DANISH 3R-CENTER
    Rasmus Normann Nielsen (Abstract ID: 452)
  • P214: THE DANISH NATIONAL COMMITTEE FOR THE PROTECTION OF ANIMALS USED FOR SCIENTIFIC PURPOSES
    Louise Holm Parby (Abstract ID: 454)
  • P216: DO WE REALLY HAVE THE SAME GENES? GENETIC DIFFERENCES BETWEEN HUMANS AND LAB MICE
    Dilyana Filipova (Abstract ID: 460)
  • P222: INTRODUCING BRAZILIAN STUDENTS TO LOBBYING - ENACTING LEGISLATION AGAINST COSMETIC TESTING ON ANIMALS
    Antoniana Ottoni (Abstract ID: 470)
  • P231: REDUCTION PROJECT ON QUALITY CONTROL POTENCY TEST FOR DIPHTHERIA AND TETANUS COMBINED VACCINE
    Blaise Descampe (Abstract ID: 481)
  • P232: RAT ACUTE SYSTEMIC TOXICITY TESTING: EVALUATING REPRODUCIBILITY AND INHERENT VARIABILITY
    Agnes Karmaus (Abstract ID: 482)
  • P241: CLASSIFICATION OF ANIMAL-DERIVED COMPONENTS FOR IN VITRO METHODS: THE XCELLR8 SCALE FOR ANIMAL-FREE TESTING
    Christopher James Longmore (Abstract ID: 499)
  • P252: GLOBAL EFFORT TO END ANIMAL TESTING FOR HEALTH CLAIMS OF FOODS AND BEVERAGES
    Frances Cheng (Abstract ID: 522)
  • P254: INTERNATIONAL HARMONIZATION OF NON-ANIMAL METHODS FOR BIOMEDICAL TRAINING
    Frances Cheng (Abstract ID: 526)
  • P255: ROADMAP TO REPLACEMENT – ADDRESSING SURPLUS ANIMAL BREEDING
    Lindsay Marshall (Abstract ID: 527)
  • P258: ADVANCES IN RECOGNIZING ALTERNATIVE METHODS IN BRAZIL
    Octavio Presgrave (Abstract ID: 531)
  • P260: NEGATIVE RESULTS OF ABNORMAL TOXICITY TEST (ATT) IN THE QUALITY CONTROL OF BIOLOGICAL PRODUCTS AT BRAZILIAN NATIONAL INSTITUTE OF QUALITY CONTROL IN HEALTH (INCQS), OSWALDO CRUZ FOUNDATION (FIOCRUZ).
    Octavio Presgrave (Abstract ID: 536)
  • P263: TITLE: WORLD PHARMACOPEIAS ARE READY TO ADOPT NON-ANIMAL IN-VITRO REPLACEMENT TESTS FOR DETECTION OF PYROGENS. ARE YOU?
    Katrin Pauls (Abstract ID: 539)
  • P267: EVALUATING DOG USE IN BIOMEDICAL RESEARCH IN ORDER TO IDENTIFY NON-ANIMAL, HUMAN-BASED REPLACEMENT OPTIONS.
    Lindsay Marshall (Abstract ID: 545)
  • P268: RETROSPECTIVE EVALUATION OF THE ACUTE FISH TOXICITY TEST FOR PESTICIDE REGISTRATION
    Patricia Ceger (Abstract ID: 546)
  • P270: CONCERNS ASSOCIATED WITH WORLD EXPANSION OF THREE RS
    Hajime Kojima (Abstract ID: 548)
  • P276: ETHICAL AND SCIENTIFIC CONCERNS REGARDING THE CONTINUED USE OF EXPERIMENTALLY INDUCED BRAIN INJURIES IN PRIMATES
    Katherine Roe (Abstract ID: 556)
  • P278: PROVIDING MEANINGFUL IN-CAGE RESOURCES FOR MICE: CONSIDERATIONS FOR NESTING MATERIAL AND A CARDBOARD SEMI-CAGE DIVIDER FOR IMPROVING MOUSE WELFARE
    Carly Moody (Abstract ID: 558)
  • P279: 3RS CENTRE IN LABORATORY ANIMAL SCIENCE IN SRI LANKA
    Mangala Gunatilake Delwatta (Abstract ID: 559)
  • P282: ANALYSIS PROCEDURES REFINEMENT IN PULMONARY ARTERIAL HYPERTENSION (PAH): RESPECT OF 3R
    Angele Gois (Abstract ID: 564)
  • P297: REFINING BEHAVIORAL MANAGEMENT PROGRAMS FOR RESEARCH PIGS
    Carly O'Malley (Abstract ID: 587)
  • P302: SYSTEMATIC REVIEW ON THE REPORTING OF MOUSE MODELS FOR BONE HEALING
    Annemarie Lang (Abstract ID: 600)
  • P304: INNOVATIVE ANIMAL-FREE TRAINING TO STEREOTAXIC NEUROSURGERY
    Damien Gervasoni (Abstract ID: 605)
  • P307: 3R-ALTERNATIVES TO SKIN TESTING OF BOVINE PPD TUBERCULINS
    Elisabeth Balks (Abstract ID: 611)
  • P320: IDENTIFYING OPTIMIZED DECISION CRITERIA AND EXPERIMENTAL DESIGNS BY SIMULATING PRECLINICAL EXPERIMENTS IN SILICO
    Meggie Danziger (Abstract ID: 634)
  • P326: GET-AWAY HOUSING FOR BREEDING LABORATORY RATS: IS TIME AWAY FROM PUPS BENEFICIAL FOR RAT DAM WELFARE?
    Anna Ratuski (Abstract ID: 643)
  • P336: EFFECTS OF TESTING MOMENT ON BEHAVIOUR AND COGNITION IN THE LABORATORY MOUSE
    Aurelie Zaros (Abstract ID: 663)
  • P340: STUDENTS’ AND RESEARCHERS’ ATTITUDES TO THE 3RS AT THE KAROLINSKA INSTITUTET – THE IMPORTANCE OF EDUCATION
    Elin Törnqvist (Abstract ID: 671)
  • P341: COMPARATIVE MEDICINE AND BIOIMAGE CENTRE OF CATALONIA: THE NEW 3RS REFERENCE CENTRE IN SPAIN
    Martí Català (Abstract ID: 672)
  • P344: ASSESSING THE UPTAKE OF RESEARCH DOG ADOPTION
    Barry Londeree (Abstract ID: 676)
  • P345: ARE DOGS STILL NEEDED IN SAFETY TESTING OF PESTICIDES?
    Patricia Bishop (Abstract ID: 681)
  • P348: CATALOGUES OF CRITERIA TO OBJECTIFY THE HARM-BENEFIT ANALYSIS OF PROPOSED ANIMAL EXPERIMENTS – AN EVOLUTION? LESSONS LEARNED DEVELOPING SUCH A CATALOGUE
    Norbert Alzmann (Abstract ID: 688)
  • P349: PIG MODEL FOR LAPAROSCOPY TRAINING: REFINEMENT OF A NON-RECOVERY ANAESTHESIA PROTOCOL
    Elisa Dalix (Abstract ID: 692)
  • P358: EVALUATION OF THE CYTOTOXICITY EFFECTS OF THE EPSILON TOXIN OFCLOSTRIDIUM PERFRINGENS ON MDCK CELLS AND ITS APPLICATION IN POTENCY TEST EVALUATION OF ENTEROTOXEMIA VACCINE
    Anahita emadi (Abstract ID: 709)
  • P359: A SURVEY OF ATTITUDES TO ALTERNATIVE METHODS TO ANIMAL EXPERIMENTATION IN SPAIN
    Amaya Azqueta (Abstract ID: 711)
  • P363: BIOBANK AT BIOMEDICAL PRIMATE RESEARCH CENTRE, THE NETHERLANDS: ATTRACTIVE ALTERNATIVE SOURCE FOR SCIENTIFIC RESEARCH
    Ivanela Kondova (Abstract ID: 720)
  • P364: VIRTUAL CLASS ON ALTERNATIVE METHODS IN TOXICOLOGY
    Francesca Caloni (Abstract ID: 724)
  • P368: JOINING FORCES TO MAP MOUSE PUP MORTALITY!
    Anna Olsson (Abstract ID: 733)
  • P371: POST-MORTEM INSPECTION OF NEW-BORN C57BL/6J MICE FOUND DEAD
    Sara Capas Peneda (Abstract ID: 736)
  • P373: NEARLY 200 MILLION ANIMALS USED IN MEDICAL RESEARCH WORLDWIDE
    Katy Taylor (Abstract ID: 739)
  • P374: THE PREVALENCE OF GAVAGE INCIDENTS IN REGULATORY TOXICITY STUDIES
    Katy Taylor (Abstract ID: 740)
  • P375: COMPLETING THE REPLACEMENT PROCESS, WHY DO SOME ANIMAL TESTS PERSIST?
    Katy Taylor (Abstract ID: 741)
  • P377: THE MONOCYTE ACTIVATION TEST AS ALTERNATIVE TO THE RABBIT PYROGEN TEST: CHOOSING THE OPTIMAL SERUM SOURCE FOR THE ASSAY
    Eelo Gitz (Abstract ID: 744)
  • P384: PEOPLE FOR ANIMAL RIGHTS-NEW CAMPAIGNING AND ACTIVITIES
    Stefanie Schindler (Abstract ID: 754)
  • P388: IPAM, THE ITALIAN PLATFORM ON ALTERNATIVE METHODS
    Isabella De Angelis (Abstract ID: 762)
  • P392: PUBLICATION AND CITATION ANALYSIS OF MEDICAL DOCTORS' MASTER THESES INVOLVING ANIMAL EXPERIMENTS ON RATS IN TURKEY
    Oguzcan Kinikoglu (Abstract ID: 771)
  • P407: SCORING 3RS ACTIVITIES OF EUROPEAN MEMBER STATES
    francois busquet (Abstract ID: 794)
  • P409: DIFFICULT PARADIGM SHIFT? REASONS FOR CONTINUED ANIMAL USE FOR EDUCATIONAL PURPOSES REVEALED IN NON-TECHNICAL SUMMARIES
    Miriam A. Zemanova (Abstract ID: 796)
  • P410: THE ETHICS OF NON-HUMAN PRIMATE RESEARCH
    Angela Hvitved (Abstract ID: 798)
  • P423: POLIO PATHOGENESIS: TRANSLATION FROM ANIMAL STUDIES TO HUMANS SETTINGS
    Ikrame Aknouch (Abstract ID: 823)
  • P424: ESTABLISHING A EUROPEAN NETWORK OF 3RS-CENTERS AND 3RS-SOCIETIES
    Horst Spielmann (Abstract ID: 825)
  • P440: ELEARNING MODULES TO PROMOTE IMPLEMENTATION AND DEVELOPMENT OF NEW ALTERNATIVE APPROACHES TO ANIMAL TESTING: CONTENT DEVELOPMENT AND POTENTIAL INTEGRATION INTO TRAINING COURSES
    Erin Hill (Abstract ID: 877)
  • P450: REDUCTION THROUGH REFINEMENT (FOR RABBITS)
    Benn Reeve (Abstract ID: 922)
  • P456: VIRTUAL PHYSIOLOGY – IN THE CLASSROOM AND FOR DISTANCE LEARNING
    Hans Albert Braun (Abstract ID: 928)
  • P466: IACUC AND ANIMAL WELFARE BODIES RESPONSIBILITIES FOR 3RS AND ROBUST IN-VIVO RESEARCH
    Gregory Reinhard (Abstract ID: 955)
  • P467: 3R'S PRINCIPLES IN ANIMAL ETHICS AND EXPERIMENTATION: HOW A METHODOLOGY TO ANALYZE MICRONUCLEUS CAN INFLUENCE THE EXCELLENCE OF LABORATORY AND REDUCE ANIMAL NUMBERS.
    Juliana Falcato Vecina (Abstract ID: 956)
  • P478: BLOOD SAMPLING FROM GÖTTINGEN MINIPIGS - IMPLEMENTING A REFINED BLOOD SAMPLING TECHNIQUE
    Kirsten Rosenmay Jacobsen (Abstract ID: 968)
  • P479: THERE IS ALWAYS AN ALTERNATIVE. A THOUGHT-STARTER TO STIMULATE AND ORGANIZE DISCUSSION OF SCIENCE-POLICY NEEDS FOR A SUSTAINABLE REGULATION OF CHEMICALS.
    Martin Paparella (Abstract ID: 969)
  • P481: NATIONAL SURVEY ON THE PROTOCOL REVIEW GUIDE APPLYING THE 3RS PRINCIPLES IN KOREA
    Gwi Hyang Lee (Abstract ID: 971)
  • P485: REFINED CARE OF NEWBORN GÖTTINGEN MINIPIGS
    Mie Johanne Hansen (Abstract ID: 977)
  • P491: DOG AS THE EXPERIMENTAL MODEL: LABORATORY USES OF DOGS IN THE UNITED STATES
    Sherry Ward (Abstract ID: 985)
  • P494: PYROGEN DETECTION IN PHARMACEUTICAL QUALITY CONTROL: MOVING AWAY FROM THE RABBIT PYROGEN TEST WITH A READY-TO-USE MONOCYTIC CELL LINE
    Laure Robert (Abstract ID: 988)
  • P497: INCREASING THE AVAILABILITY AND QUALITY OF HUMAN TISSUE FOR RESEARCH
    Janine McCarthy (Abstract ID: 992)
  • P521: A SURVEY ON THE USE OF ANIMAL-DERIVED MATERIALS AND REAGENTS IN SCIENTIFIC EXPERIMENTATION
    Manuela Cassotta (Abstract ID: 1020)
  • P522: ADOPTING EU RESEARCH CATEGORY/SUBCATEGORY NOMENCLATURE TO CATEGORIZE RESEARCH USES OF DOGS
    Sherry Ward (Abstract ID: 1021)
  • P527: 3RS INFO HUB
    Vivian Kral (Abstract ID: 1031)
  • P528: EFFECT OF GNAWING WOOD ENRICHMENT ON DISEASE INDUCTION IN A MOUSE MODEL FOR DIET-INDUCED NASH
    Geurt Stokman (Abstract ID: 1033)
  • P529: ASSOCIATIONS BETWEEN CLINICAL SIGNS AND PATHOLOGICAL FINDINGS IN TOXICITY TESTING
    Antero Vieira da Silva (Abstract ID: 1034)
  • P530: ACCELERATING THE UPTAKE OF NON ANIMAL METHODS IN BIOSCIENCE RESEARCH: SYSTEM DYNAMICS AND INDIVIDUAL RESPONSIBILITY
    Celean Camp (Abstract ID: 1036)
  • P531: EXTENSION OF THE PERFORMANCE STATISTICS OF DEFINED APPROACHES TO DISTINGUISH BETWEEN THE THREE UN GHS CATEGORIES FOR EYE HAZARD IDENTIFICATION AND BEYOND
    Arianna Giusti (Abstract ID: 1037)
  • P532: IS IT POSSIBLE TO STEM THE TIDE OF GA ANIMAL USE IN BIOMEDICAL RESEARCH?
    Amy Beale (Abstract ID: 1038)
  • P534: RESOURCES & INITIATIVES FOR REFINING, REDUCING, AND REPLACING ANIMALS IN RESEARCH
    Megan Renee LaFollette (Abstract ID: 1041)
  • P536: PERFORMANCE STATISTICS OF DEFINED APPROACHES FOR EYE HAZARD IDENTIFICATION OF LIQUIDS TO DISTINGUISH BETWEEN THE THREE UN GHS CATEGORIES
    Arianna Giusti (Abstract ID: 1043)
  • P551: EFFECT OF COOLING AS AN ANAESTHETIC METHOD FOR ZEBRAFISH (DANIO RERIO)
    Prasadi Nayanashani De Silva (Abstract ID: 1061)
  • P557: OEM/ODM ENTERPRISE ESTABLISHES ALTERNATIVE METHOD PLATFORM
    Tingting Luo (Abstract ID: 1068)
  • P558: THE DEVELOPMENT OF ALTERNATIVE METHODS IN CHINA AND THE ROLE OF THE INDUSTRIES
    Shujun Cheng (Abstract ID: 1069)
  • P563: CHALLENGES IN DEVELOPING AN ONLINE ANIMAL ETHICS COURSE
    Josephine Joya (Abstract ID: 1075)
  • P583: LACK OF ENFORCEMENT ACTIONS BY USDA AGAINST RESEARCH FACILITIES USING ANIMALS
    Mary Hilley (Abstract ID: 1102)
  • P585: COOPERATIVE TRAINING IS AN OPPORTUNITY FOR REFINEMENT THAT ELIMINATES RESTRAINT AS A SOURCE OF VARIATION AND CONFOUNDING TO IMPROVE THE PREDICTIVE VALUE OF PRIMATE MODELS
    Scott Hunter Oppler Jr (Abstract ID: 1106)

 

Theme 4: Disease

  • P3: PROTECTIVE EFFECT OF MELATONIN ON HYPOXIA-INDUCED CARDIOMYOCYTE DIFFERENTIATION OF MOUSE EMBRYONIC STEM CELLS
    Eui-Bae Jeung (Abstract ID: 33)
  • P21: MONITORING INNOVATION AND SOCIETAL IMPACT OF BIOMEDICAL RESEARCH
    Janine McCarthy (Abstract ID: 117)
  • P24: CORNEAL EDEMA SIMULATION AND THERAPY IN THE EX VIVO EYE IRRITATION TEST (EVEIT)
    Markus Glaudo (Abstract ID: 123)
  • P43: ZEBRAFISH: A POWERFUL ALTERNATIVE MODEL FOR RARE NEURODEGENERATIVE/NEUROMUSCULAR DISEASES
    Ane Altuna (Abstract ID: 160)
  • P49: CERTAIN HARMS AND UNCERTAIN BENEFITS IN ANIMAL MODELS FOR THE STUDY OF HUMAN DEPRESSION AND ANXIETY
    Emily R. Trunnell (Abstract ID: 173)
  • P51: THE EVALUATION OF CHO CELL CLUSTERING ASSAY TO TEST FOR PERTUSSIS TOXIN USING AUTOMATIC WHOLE WELL IMAGE CAPTURE AND ANALYSIS
    Masaki Ochiai (Abstract ID: 176)
  • P55: IN VITRO ANTITUMOR ACTIVITY OF A NOVEL ORGANOSELENIUM COMPOUND VIA TRANSFERRIN-CONJUGATED PLGA NANOPARTICLES
    Maria Pilar Vinardell (Abstract ID: 181)
  • P56: HUMAN MODEL SYSTEM FOR STUDYING THE EFFECTS OF LIFESTYLE ASSOCIATED CELLULAR STRESSORS IN TYPE 2 DIABETES.
    Nicola M Jeffery (Abstract ID: 182)
  • P57: IN VITRO PREDICTION OF IN VIVO PSEUDO-ALLERGENIC RESPONSE VIA MRGPRX2
    Thomas Bertelsen (Abstract ID: 184)
  • P59: 3D SPHEROIDS OF CHORIORETINAL ENDOTHELIAL CELLS AS AN ALTERNATIVE-TO-ANIMAL MODEL FOR DIABETIC RETINOPATHY
    Manish Gore (Abstract ID: 190)
  • P69: DISEASE RESEARCH WITHOUT ANIMAL RESEARCH
    Jarrod Bailey (Abstract ID: 208)
  • P70: TRANSLATABILITY OF NHP RESEARCH AND TESTING TO THE DEVELOPMENT OF HIV/AIDS VACCINES
    Jarrod Bailey (Abstract ID: 209)
  • P73: SCREENING IN IPSC DERIVED NEURONS FOR MODIFIERS OF ALZHEIMER’S RELATED PHENOTYPES
    Shushant jain (Abstract ID: 214)
  • P77: SYSTEMATIC REVIEW PROTOCOL ON THE EFFECT OF FECAL MICROBIOTA TRANSPLANTATION ON BEHAVIOUR IN ANIMALS
    Erin Colleen Boyle (Abstract ID: 218)
  • P82: SEARCH FOR CANDIDATE MIRNAS IMPLICATED IN PUTATIVE ADVERSE OUTCOME PATHWAY (AOP) RELEVANT TO ALZHEIMER’S DISEASE
    Maria Tsamou (Abstract ID: 225)
  • P108: GALLERIA MELLONELLA MODEL HOST: A POTENTIAL IN VIVO TOOL TO ASSESS ANTIBODY FUNCTIONALITY
    Emiliano Chiarot (Abstract ID: 278)
  • P109: APOPTOSIS AND AUTOPHAGY CAN BE REDUCED WITH AN INOS-INHIBITOR IN AN OXIDATIVE STRESS RETINA ORGAN CULTURE MODEL
    Sven Schnichels (Abstract ID: 280)
  • P127: ACTIVITIES CONTRIBUTING TO THE DELETION OF THE ANIMAL TEST FOR IRREVERSIBILITY OF TETANUS TOXOIDS
    Heike Behrensdorf-Nicol (Abstract ID: 315)
  • P131: THE BINACLE (BINDING AND CLEAVAGE) ASSAY FOR MEASURING THE ACTIVITY OF BOTULINUM NEUROTOXIN IN VITRO
    Heike Behrensdorf-Nicol (Abstract ID: 319)
  • P141: ONCOCHIP: DEVELOPMENT OF A MICROFLUIDIC HUMAN TEST PLATFORM FOR IMMUNE-ONCOLOGY THERAPY TESTING
    Anna-Catharina Krebs (Abstract ID: 335)
  • P172: ZEBRAFISH EMBRYO MODEL FOR CHEMICAL-INDUCED CRANIOFACIAL ANOMALIES
    Junichi Tasaki (Abstract ID: 393)
  • P178: 95% REDUCTION IN THE USE OF HORSESHOE CRAB BLOOD THANKS TO AUTOMATED ENDOTOXIN LIMULUS AMEBOCYTE LYSATE (LAL)
    Marion Valle (Abstract ID: 400)
  • P182: DEFINING SIMILARITY OF CHEMICAL COMPOUNDS BY MEANS OF AUTOMATED TEXT MINING
    Chris Bauer (Abstract ID: 404)
  • P183: DEVELOPMENT AND CHARACTERIZATION OF 3D SPHEROIDS FOR PRE-CLINICAL APPLICATION
    Tejal Pant (Abstract ID: 405)
  • P194: ANIMAL-FREE METHOD TO TEST PYROGENICITY OF TICK-BORNE ENCEPHALITIS VIRUS (TBEV) HUMAN VACCINE
    Shahjahan Shaid (Abstract ID: 424)
  • P207: BEYOND THE USE OF EQUINES IN ANTITOXIN PRODUCTION
    Dipti Malhotra Kapoor (Abstract ID: 446)
  • P209: STUDYING TRANSITION STATES OF DISEASE IN AN IN VITRO CELL SYSTEM FOR NAFLD
    Charlie Pieterman (Abstract ID: 448)
  • P215: NORMOTHERMIC MACHINE PERFUSION OF HUMAN DISEASED EX VIVO LIVERS TO STUDY HEPATIC PHARMACOKINETIC PROCESSES
    Lianne Stevens (Abstract ID: 457)
  • P234: DEVELOPMENT OF AN INTESTINAL ORGANOID-BASED PLATFORM FOR SCREENING ANTIVIRAL AGENTS
    Ludovico Buti (Abstract ID: 485)
  • P236: EVALUATION OF THE CAPACITY OF INTESTINAL CELL LINES TO RESPOND TO IMMUNE STIMULI
    Menno Grouls (Abstract ID: 487)
  • P237: RABIES 2+1 SEQUENTIAL TESTING TO REDUCE 40% OF THE USE OF ANIMALS
    Roman Adamczyk (Abstract ID: 489)
  • P238: TBE SINGLE-DILUTION AS VIRAL VACCINE POTENCY TESTING TO REDUCE 70% OF THE USE OF ANIMALS
    Roman Adamczyk (Abstract ID: 491)
  • P247: HUMAN IN VITRO MODELS TO STUDY BONE METASTASES
    Marjolein van Driel (Abstract ID: 515)
  • P248: THE DEVELOPMENT OF A REPEATED WHOLE AEROSOL EXPOSURE ASSAY USING HUMAN BRONCHIAL EPITHELIUM IN VITRO TO STUDY THE EFFECT OF CIGARETTE SMOKE AND TOBACCO HEATED PRODUCTS
    Linsey Ellen Haswell (Abstract ID: 516)
  • P251: COMPARISON OF TOXICITY OF COMBUSTIBLE CIGARETTE AND A NOVEL TOBACCO HEATING PRODUCT BY TOXTRACKER.
    David Smart (Abstract ID: 521)
  • P265: CONFIRMATORY PRECLINICAL STUDIES AS MEANS TO GUIDE DECISIONS TO ENGAGE IN CLINICAL TRIALS: THE DECIDE PROJECT
    Ulf Tölch (Abstract ID: 541)
  • P292: DEVELOPMENT OF AN EX-VIVO RETINAL DYSTROPHY MODEL BY LIGHT INDUCED NEURODEGENERATION
    Jose Hurst (Abstract ID: 577)
  • P298: HUMAN AUTOLOGOUS 3D SARCOMA TUMOR MODELS
    Beate Rinner (Abstract ID: 589)
  • P305: COMPARING HUMAN CELL LINE CO-CULTURES AND PORCINE ORGANOIDS: STUDYING (PATHO)PHYSIOLOGICAL INTESTINAL MECHANISMS
    Pascal Hoffmann (Abstract ID: 606)
  • P314: TRANSEPITHELIAL ELECTRICAL RESISTANCE AS A FAST READ-OUT OF IN VITRO AND EX VIVO MODELS MIMICKING THE GI-TRACT INFLAMMATION
    Sabrina Schnur (Abstract ID: 623)
  • P328: ZEBRAFISH EMBRYO MODEL FOR CHEMICAL-INDUCED CLEFT PALATE.
    Junichi Tasaki (Abstract ID: 646)
  • P337: ENDOMETRIOSIS: CURRENT CHALLENGES IN MODELING A MULTIFACTORIAL DISEASE OF UNKNOWN ETIOLOGY
    Helena Malvezzi (Abstract ID: 664)
  • P352: N VITRO PROPERTIES SCREENING OF NATURAL COMPOSITES FOR SMART WOUND PATCHES
    Rosalia Bertorelli (Abstract ID: 699)
  • P379: DEVELOPMENT OF FUNCTIONAL 3D CARDIOVASCULAR CONSTRUCT
    Hanna Vuorenpää (Abstract ID: 749)
  • P389: EXPANDING THE APPLICABILITY OF PRIMARY HUMAN HEPATOCYTE SPHEROIDS TO THE ASSESSMENT OF THE CHOLESTATIC LIABILITY OF CHEMICALS
    Vânia Vilas-Boas (Abstract ID: 763)
  • P408: TRANSMEMBRANE PROTEIN SMOOTHENED IS CLEAVED AND SIGNALS WITHIN THE NUCLEUS
    Muhammad Rahman (Abstract ID: 795)
  • P414: TRANSMEMBRANE PROTEIN SMOOTHENED IS CLEAVED AND SIGNALS WITHIN THE NUCLEUS
    Muhammad Rahman (Abstract ID: 802)
  • P432: REVIEW OF ANIMAL TESTING REQUIREMENTS IN WHO GUIDELINES AND RECOMMENDATIONS FOR BIOLOGICS: A PROPOSAL TO IMPLEMENT 3RS PRINCIPLES
    Elliot Lilley (Abstract ID: 841)
  • P433: THE IMPORTANCE OF SIMULATED LUNG FLUID COMPOSITION FOR IN VITRO SOLUBILITY OF MINERAL WOOL FIBERS
    Natasa Drnovsek (Abstract ID: 843)
  • P435: MICROFLUIDIC LUNG-LIVER-GUT AXIS - A PLATFORM FOR STUDIES ON HOST-MICROBIOTA INTERACTION
    Alexander Mosig (Abstract ID: 864)
  • P442: INVESTIGATION OF PERSISTENCE & METABOLIC ADAPTION OF STAPHYLOCOCCUS AUREUS IN A IMMUNOCOMPETENT LIVER-ON-CHIP MODEL
    Fatina Siwczak (Abstract ID: 879)
  • P452: A NOVEL EPIDERMIS EQUIVALENT FOR IN VITRO SKIN IRRITATION TESTING: CHARACTERIZATION AND PERFORMANCE
    Daniela Morais Leme (Abstract ID: 924)
  • P453: RECOMBINANT ANTIBODIES: RIPE FOR REPLACEMENT
    Charu Chandrasekera (Abstract ID: 925)
  • P454: PREDICTION OF AN ADAPTIVE IMMUNE RESPONSE BY CHARACTERIZATION OF T CELL MARKER IN A CO-CULTIVATION SYSTEM
    Sinja-Fee Schramm (Abstract ID: 926)
  • P462: AN INNOVATIVE MILLIFLUIDIC 3D HUMAN TRABECULAR CELL IN VITRO PLATFORM AS TOOL TO MIMIC THE PRESSURE VARIATIONS OBSERVED IN OPEN ANGLE GLAUCOMA
    Anna Maria Bassi (Abstract ID: 941)
  • P469: DEVELOPMENT OF A LIVER CARCINOMA BIOMARKER PANEL IN 3D HEPG2 LIVER SPHEROIDS FOLLOWING EXPOSURE TO NANOMATERIALS
    Gillian E Conway (Abstract ID: 958)
  • P474: ASSESSMENT OF COOLING EFFECTS OF TOPICAL PRODUCTS ON HUMAN SKIN IN VITRO
    Udo Bock (Abstract ID: 964)
  • P498: IMMUNOGENICITY STUDIES OF PRE- AND POST-EXPOSURE ANTI-RABIES VACCINATION (ARV) USING BALB/C MICE: A SYSTEMATIC REVIEW
    Hasanthi Rathnadiwakara (Abstract ID: 993)
  • P533: PRECISION-CUT LUNG SLICES AND REFINED CLINICAL READOUTS IN HAMSTER MODEL SUPPORT THE 3RS IN CORONAVIRUS RESEARCH
    Nadia Oreshkova (Abstract ID: 1040)
  • P539: BREAST MILK INHIBITS ENVELOPED VIRUS INFECTION, INCLUDING SARS-COV-2, IN A HUMAN GUT ENTEROID MODEL
    Ikrame Aknouch (Abstract ID: 1046)
  • P548: MODULATION OF P2X7 RECEPTOR USING QUERCETIN: ROLE IN COVID-19 INFLAMMATION MANAGEMENT?
    Elodie OLIVIER (Abstract ID: 1057)
  • P575: CONTACTLESS BODY TEMPERATURE ASSESSMENT FOR DETERMINING HUMANE ENDPOINTS IN THE CECAL LIGATION AND PUNCTURE MODEL OF SEPSIS
    Catarina Silva Miranda (Abstract ID: 1092)